Enantioselective aryl-aryl coupling facilitated by chiral binuclear gold complexes

被引：16
|
作者：
Himmelstrup, Jonas [1 ]
Buendia, Mikkel B. [1 ]
Sun, Xing-Wen [2 ]
Kramer, Soren [1 ]
机构：
[1] Tech Univ Denmark, Dept Chem, DK-2800 Lyngby, Denmark
[2] Fudan Univ, Dept Chem, 220 Handan Rd, Shanghai 200433, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2019年 / 55卷 / 86期
关键词：
C-H ACTIVATION; DUAL GOLD; PHOTOREDOX; ATROPISOMERS; CATALYSIS; ARENES; CONSTRUCTION; SELECTIVITY; SALTS; ACIDS;
D O I：
10.1039/c9cc07175j
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Herein, we report stoichiometric investigations embodying the first highly enantioselective aryl-aryl coupling facilitated by a gold complex. With up to 91% ee, this is the first demonstration of a transmetalation and C(sp(2))-C(sp(2)) reductive elimination sequence with high enantioselectivity using a gold complex. The results offer a basis for development of enantioselective gold-catalyzed aryl-aryl coupling reactions.
引用
收藏
页码：12988 / 12991
页数：4
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