Cerebral Sinus Thrombosis and Heparin-induced Thrombocytopenia in a Patient with Paroxysmal Nocturnal Hemoglobinuria

被引：4

作者：

Ishihara-Kawase, Kayoko ^{[1
]}

Ohtsuki, Toshiho ^{[1
]}

Sugihara, Sayaka ^{[2
]}

Tanaka, Hitomi ^{[1
]}

Nakamura, Takeshi ^{[1
]}

Kimura, Akiro ^{[2
]}

Matsumoto, Masayasu ^{[1
]}

机构：

[1] Hiroshima Univ, Grad Sch Biomed Sci, Dept Clin Neurosci & Therapeut, Hiroshima, Japan

[2] Hiroshima Univ, Grad Sch Biomed Sci, Dept Hematol & Oncol, Div Clin & Expt Oncol,Res Inst Radiat Biol & Med, Hiroshima, Japan

来源：

INTERNAL MEDICINE | 2010年 / 49卷 / 10期

关键词：

cerebral venous thrombosis; stroke in young adults; hematology; DIAGNOSIS; SCORE;

D O I：

10.2169/internalmedicine.49.3053

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Paroxysmal nocturnal hemoglobinuria is a rare acquired disorder of clonal hematopoietic stem cells and it is characterized as a hypercoagulable disorder. We report a 36-year-old woman with the rare triad of paroxysmal nocturnal hemoglobinuria, cerebral sinus thrombosis triggered by infection, and rapid-onset heparin-induced thrombocytopenia after resensitization of heparin. This case raises caution for heparin-induced thrombocytopenia in paroxysmal nocturnal hemoglobinuria.

引用

页码：941 / 943

页数：3

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