Cerebral Sinus Thrombosis and Heparin-induced Thrombocytopenia in a Patient with Paroxysmal Nocturnal Hemoglobinuria

被引:4
|
作者
Ishihara-Kawase, Kayoko [1 ]
Ohtsuki, Toshiho [1 ]
Sugihara, Sayaka [2 ]
Tanaka, Hitomi [1 ]
Nakamura, Takeshi [1 ]
Kimura, Akiro [2 ]
Matsumoto, Masayasu [1 ]
机构
[1] Hiroshima Univ, Grad Sch Biomed Sci, Dept Clin Neurosci & Therapeut, Hiroshima, Japan
[2] Hiroshima Univ, Grad Sch Biomed Sci, Dept Hematol & Oncol, Div Clin & Expt Oncol,Res Inst Radiat Biol & Med, Hiroshima, Japan
关键词
cerebral venous thrombosis; stroke in young adults; hematology; DIAGNOSIS; SCORE;
D O I
10.2169/internalmedicine.49.3053
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Paroxysmal nocturnal hemoglobinuria is a rare acquired disorder of clonal hematopoietic stem cells and it is characterized as a hypercoagulable disorder. We report a 36-year-old woman with the rare triad of paroxysmal nocturnal hemoglobinuria, cerebral sinus thrombosis triggered by infection, and rapid-onset heparin-induced thrombocytopenia after resensitization of heparin. This case raises caution for heparin-induced thrombocytopenia in paroxysmal nocturnal hemoglobinuria.
引用
收藏
页码:941 / 943
页数:3
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