Congenital fulminant Kaposiform hemangioendothelioma of the leg

被引:0
|
作者
Ergaz, Zivanit [1 ]
Bar-Oz, Benjamin [1 ]
Vainer, Gilad W. [2 ]
Abu-Leil, Sinan [1 ]
Simanovsky, Natalia [3 ]
Diav-Citrin, Orna [4 ]
机构
[1] Hadassah Hebrew Univ Med Ctr, Dept Neonatol, Jerusalem, Israel
[2] Tel Aviv Univ, Tel Aviv Sourasky Med Ctr, Dept Pathol, IL-69978 Tel Aviv, Israel
[3] Hadassah Hebrew Univ Med Ctr, Dept Med Imaging, Jerusalem, Israel
[4] Israel Minist Hlth, Israeli Teratol Informat Serv, Jerusalem, Israel
关键词
Etanercept; Kaposiform hemangioendothelioma; Kasabach Merritt syndrome; Congenital; Multi-organ failure; PREGNANCY; INHIBITORS; SAFETY;
D O I
10.1016/j.reprotox.2014.09.011
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Kaposiform hemangioendothelioma is a rare locally aggressive vascular tumor associated with Kasabach Merritt syndrome. We present a case of congenital Kaposiform hemangioendothelioma of the leg in a female infant who was born to a mother treated with various medications including etanercept, a TNF antagonist, due to rheumatoid arthritis. The neonate suffered from a fulminant form of Kasabach Merritt syndrome with disseminated intravascular coagulation (DIC) resulting in multi-organ failure which led to her demise. (C) 2014 Elsevier Inc. All rights reserved.
引用
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页码:1 / 3
页数:3
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