Label-Free Imaging of Single Neuron Activities by Stimulated Raman Scattering

被引：0
|
作者：
Zhang, Delong [1 ]
Lee, Hyeon Jeong [2 ]
Shih, Pei-Yu [3 ]
Drenan, Ryan E. [3 ]
Cheng, Ji-Xin [1 ]
机构：
[1] Purdue Univ, Weldon Sch Biomed Engn, W Lafayette, IN 47906 USA
[2] Purdue Univ, Dept Comparat Pathobiol, W Lafayette, IN 47906 USA
[3] Purdue Univ, Dept Med Chem & Mol Pharmacol, W Lafayette, IN 47906 USA
来源：
2015 CONFERENCE ON LASERS AND ELECTRO-OPTICS (CLEO) | 2015年
关键词：
D O I：
暂无
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
We report the observation of single neuron activities by spectral focusing stimulated Raman scattering (SRS) microscopy. Changes in SRS signal intensity in live neurons correlate to action potentials indicated by fluorescent calcium indicator.
引用
收藏
页数：2
相关论文
共 50 条
  • [21] Label-Free Imaging of Lipid Storage Dynamics in Caenorhabditis elegans using Stimulated Raman Scattering Microscopy
    Mutlu, Ayse Sena
    Chen, Tao
    Deng, Dinghuan
    Wang, Meng C.
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2021, (171):
  • [22] Polarization-resolved hyperspectral stimulated Raman scattering microscopy for label-free biomolecular imaging of the tooth
    Wang, Zi
    Zheng, Wei
    Hsu, Chin-Ying Stephen
    Huang, Zhiwei
    APPLIED PHYSICS LETTERS, 2016, 108 (03)
  • [23] In situ label-free imaging of hemicellulose in plant cell walls using stimulated Raman scattering microscopy
    Yining Zeng
    John M. Yarbrough
    Ashutosh Mittal
    Melvin P. Tucker
    Todd B. Vinzant
    Stephen R. Decker
    Michael E. Himmel
    Biotechnology for Biofuels, 9
  • [24] In situ label-free imaging of hemicellulose in plant cell walls using stimulated Raman scattering microscopy
    Zeng, Yining
    Yarbrough, John M.
    Mittal, Ashutosh
    Tucker, Melvin P.
    Vinzant, Todd B.
    Decker, Stephen R.
    Himmel, Michael E.
    BIOTECHNOLOGY FOR BIOFUELS, 2016, 9
  • [25] Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy
    Ji, Minbiao
    Orringer, Daniel A.
    Freudiger, Christian W.
    Ramkissoon, Shakti
    Liu, Xiaohui
    Lau, Darryl
    Golby, Alexandra J.
    Norton, Isaiah
    Hayashi, Marika
    Agar, Nathalie Y. R.
    Young, Geoffrey S.
    Spino, Cathie
    Santagata, Sandro
    Camelo-Piragua, Sandra
    Ligon, Keith L.
    Sagher, Oren
    Xie, X. Sunney
    SCIENCE TRANSLATIONAL MEDICINE, 2013, 5 (201)
  • [26] Label-free spectroscopic detection of membrane potential using stimulated Raman scattering
    Liu, Bin
    Lee, Hyeon Jeong
    Zhang, Delong
    Liao, Chien-Sheng
    Ji, Na
    Xia, Yuanqin
    Cheng, Ji-Xin
    APPLIED PHYSICS LETTERS, 2015, 106 (17)
  • [27] Quantitative Label-Free Imaging of Lipid Domains in Single Bilayers by Hyperspectral Coherent Raman Scattering
    Nahmad-Rohen, Alexander
    Regan, David
    Masia, Francesco
    McPhee, Craig
    Pope, Iestyn
    Langbein, Wolfgang
    Borri, Paola
    ANALYTICAL CHEMISTRY, 2020, 92 (21) : 14657 - 14666
  • [28] Coherent Raman scattering microscopy for label-free imaging of live amphioxus
    Yu, Zhilong
    Chen, Tao
    Zhang, Xiannian
    Shen, Jie
    Chen, Junyuan
    Huang, Yanyi
    MULTIPHOTON MICROSCOPY IN THE BIOMEDICAL SCIENCES XII, 2012, 8226
  • [29] Label-free imaging of lipid dynamics using Coherent Anti-stokes Raman Scattering (CARS) and Stimulated Raman Scattering (SRS) microscopy
    Folick, Andrew
    Min, Wei
    Wang, Meng C.
    CURRENT OPINION IN GENETICS & DEVELOPMENT, 2011, 21 (05) : 585 - 590
  • [30] Label-Free Imaging of Lipid Droplets in Prostate Cells Using Stimulated Raman Scattering Microscopy and Multivariate Analysis
    Hislop, Ewan W.
    Tipping, William J.
    Faulds, Karen
    Graham, Duncan
    ANALYTICAL CHEMISTRY, 2022, 94 (25) : 8899 - 8908
12345