Rapid and Sensitive Detection of Microcystin-LR using THz-Aptamer Biosensor

被引：0
|
作者：
Mohamed, Ahmed [1 ]
Walsh, Ryan [2 ]
Ropagnol, Xavier [1 ]
Perreault, Jonathan [2 ]
Ozaki, Tsuneyuki [1 ]
机构：
[1] Nstitut Natl Rech Sci Energie Mat Telecommun, Varennes, PQ J3X 1S2, Canada
[2] INRS Ctr Armand Frappier Sante Biotechnol, Laval, PQ H7V 1B7, Canada
来源：
2021 46TH INTERNATIONAL CONFERENCE ON INFRARED, MILLIMETER AND TERAHERTZ WAVES (IRMMW-THZ) | 2021年
关键词：
D O I：
10.1109/IRMMW-THz50926.2021.9567267
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
A combination of Terahertz (THz) emission and aptamer technologies has a crucial impact on the highly sensitive and rapid detection of small toxic molecules such as microcystin-LR (MC-LR). THz chemical microscope (TCM) is a unique THz aptasensor that has been successfully used for monitoring MC-LR molecules in buffer and complex samples. Our results show that our TCM aptasensor has an excellent detection limit of 50 ng/L as well as the assay time is about 15 min. Compared with other biosensors such as surface plasmon resonance (SPR), our TCM aptasensor provides a rapid and sensitive assay.
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