Rapid and Sensitive Detection of Microcystin-LR using THz-Aptamer Biosensor

被引：0
|
作者：
Mohamed, Ahmed [1 ]
Walsh, Ryan [2 ]
Ropagnol, Xavier [1 ]
Perreault, Jonathan [2 ]
Ozaki, Tsuneyuki [1 ]
机构：
[1] Nstitut Natl Rech Sci Energie Mat Telecommun, Varennes, PQ J3X 1S2, Canada
[2] INRS Ctr Armand Frappier Sante Biotechnol, Laval, PQ H7V 1B7, Canada
来源：
2021 46TH INTERNATIONAL CONFERENCE ON INFRARED, MILLIMETER AND TERAHERTZ WAVES (IRMMW-THZ) | 2021年
关键词：
D O I：
10.1109/IRMMW-THz50926.2021.9567267
中图分类号：
TM [电工技术]; TN [电子技术、通信技术];
学科分类号：
0808 ; 0809 ;
摘要：
A combination of Terahertz (THz) emission and aptamer technologies has a crucial impact on the highly sensitive and rapid detection of small toxic molecules such as microcystin-LR (MC-LR). THz chemical microscope (TCM) is a unique THz aptasensor that has been successfully used for monitoring MC-LR molecules in buffer and complex samples. Our results show that our TCM aptasensor has an excellent detection limit of 50 ng/L as well as the assay time is about 15 min. Compared with other biosensors such as surface plasmon resonance (SPR), our TCM aptasensor provides a rapid and sensitive assay.
引用
收藏
页数：1
相关论文
共 50 条
  • [1] Label-free aptamer-based detection of microcystin-LR using a microcantilever array biosensor
    Zhang, Guanping
    Li, Chao
    Wu, Shangquan
    Zhang, Qingchuan
    SENSORS AND ACTUATORS B-CHEMICAL, 2018, 260 : 42 - 47
  • [2] Novel signal-on immunosensors for rapid and sensitive detection of Microcystin-LR
    Zhang, Liqian
    Dong, Hang
    Li, Haimei
    Li, Baowei
    Zhao, Guangwei
    Cai, Hongling
    Chen, Limei
    Dong, Jinhua
    MICROCHEMICAL JOURNAL, 2021, 167
  • [3] Recent Advancement of Biosensor Technology for the Detection of Microcystin-LR
    Pang, Pengfei
    Lai, Yanqiong
    Zhang, Yanli
    Wang, Hongbin
    Conlan, Xavier A.
    Barrow, Colin J.
    Yang, Wenrong
    BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 2020, 93 (05) : 637 - 646
  • [4] Highly Sensitive and Rapid Detection of Microcystin-LR in Source and Finished Water Samples Using Cantilever Sensors
    Ding, Yanjun
    Mutharasan, Raj
    ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2011, 45 (04) : 1490 - 1496
  • [5] Sensitive Identification of Microcystin-LR via a Reagent-Free and Reusable Electrochemical Biosensor Using a Methylene Blue-Labeled Aptamer
    Wei, Xiaoqian
    Wang, Shanlin
    Zhan, Yujuan
    Kai, Tianhan
    Ding, Ping
    BIOSENSORS-BASEL, 2022, 12 (08):
  • [6] Phosphorescent immunosensor for simple and sensitive detection of microcystin-LR in water
    Qin, Jin
    Sun, Xiaojie
    Li, Dongxia
    Yan, Guiqin
    RSC ADVANCES, 2019, 9 (22): : 12747 - 12754
  • [7] Rapid chemiluminescence biosensing of microcystin-LR
    Lindner, Petra
    Molz, Ramona
    Yacoub-George, Erwin
    Wolf, Hans
    ANALYTICA CHIMICA ACTA, 2009, 636 (02) : 218 - 223
  • [8] High-sensitivity small-molecule detection of microcystin-LR cyano-toxin using a terahertz-aptamer biosensor
    Mohamed, Ahmed
    Walsh, Ryan
    Cherif, Mohamed
    Hafez, Hassan A.
    Ropagnol, Xavier
    Vidal, Francois
    Perreault, Jonathan
    Ozaki, Tsuneyuki
    ANALYST, 2021, 146 (24) : 7583 - 7592
  • [9] Sensitive and rapid chemiluminescence enzyme immunoassay for microcystin-LR in water samples
    Long, F.
    Shi, H. C.
    He, M.
    Sheng, J. W.
    Wang, J. F.
    ANALYTICA CHIMICA ACTA, 2009, 649 (01) : 123 - 127
  • [10] Determination of microcystin-LR in water by a label-free aptamer based electrochemical impedance biosensor
    Lin, Zhenyu
    Huang, Huiming
    Xu, Yixiang
    Gao, Xiaoyao
    Qiu, Bin
    Chen, Xi
    Chen, Guonan
    TALANTA, 2013, 103 : 371 - 374
12345