X-ray micro-CT scanner for small animal imaging based on Timepix detector technology

被引：16
|
作者：
Dudak, Jan [1 ,2 ]
Zemlicka, Jan [1 ]
Krejci, Frantisek [1 ]
Polansky, Stepan [1 ]
Jakubek, Jan [1 ]
Mrzilkova, Jana [3 ]
Patzelt, Matej [3 ]
Trnka, Jan [3 ]
机构：
[1] Czech Tech Univ, Inst Expt & Appl Phys, Prague 12800 2, Czech Republic
[2] Czech Tech Univ, Fac Biomed Engn, Kladno 27200, Czech Republic
[3] Charles Univ Prague, Fac Med 3, Prague 10000, Czech Republic
来源：
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT | 2015年 / 773卷
关键词：
Computerized tomography; Hybrid detector; Timepix; Small animal imaging; COMPUTED TOMOGRAPHY; MICROTOMOGRAPHY; RESOLUTION;
D O I：
10.1016/j.nima.2014.10.076
中图分类号：
TH7 [仪器、仪表];
学科分类号：
0804 ; 080401 ; 081102 ;
摘要：
We describe a newly developed compact micro-CT scanner with rotating gantry equipped with a Timepix Quad hybrid pixel semiconductor detector and a micro-focus X-ray tube providing spatial resolution down to 30 mu m. The resolving power of the device in relation to soft tissue sensitivity is demonstrated using a tissue-equivalent phantom and different types of biological samples. The results demonstrate that the use of noiseless particle counting detectors is a promising way to achieve sufficient soft tissue contrast even without any contrast agents. (C) 2014 Elsevier B.V. All rights reserved.
引用
收藏
页码：81 / 86
页数：6
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