Lactic Acidosis Associated With Metformin in a Patient With Type 2 Diabetes With No Contraindication

被引：2
|
作者：
Dora, Jose Miguel [1 ]
de Souza, Livia H. [1 ]
de Azevedo, Mirela J. [1 ]
Gross, Jorge L. [1 ]
机构：
[1] Univ Fed Rio Grande do Sul, Hosp Clin Porto Alegre, Serv Endocrinol, Div Endocrine, BR-90035003 Porto Alegre, RS, Brazil
来源：
ENDOCRINOLOGIST | 2009年 / 19卷 / 06期
关键词：
metformin; biguanides; lactic acidosis; type; 2; diabetes; OUTCOMES;
D O I：
10.1097/TEN.0b013e3181bf1e2e
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Metformin is a frequent treatment for overweight type 2 patients with diabetes. Lactic acidosis (LA) is considered to be a rare, but potentially lethal adverse event associated with metformin. We describe a 52-year-old diabetic patient, with no contra indication to metformin, who had an unequivocal episode of LA related to the drug. After intensive supportive treatment, a fast recovery was observed. Considering putative benefits attributed to metformin, contraindications to this drug are being debated. The association of metformin with LA should be kept in mind when dealing with acute situations such as that presented by the patient described.
引用
收藏
页码：250 / 250
页数：1
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