A scanned, focused, multiple transducer ultrasonic system for localized hyperthermia treatments

被引:10
|
作者
Hynynen, K. [1 ]
Roemer, R. [1 ,2 ]
Anhalt, D. [3 ]
Johnson, C. [3 ]
Xu, Z. X. [2 ]
Swindell, W. [1 ]
Cetas, T. [1 ]
机构
[1] Univ Arizona, Arizona Hlth Sci Ctr, Dept Radiat Oncol, Tucson, AZ 85724 USA
[2] Univ Arizona, Dept Aerosp & Mech Engn, Tucson, AZ 85721 USA
[3] Univ Arizona, Dept Elect & Comp Engn, Tucson, AZ 85721 USA
关键词
hyperthermia; ultrasound; focused fields; temperature distribution; deep heating; DISTRIBUTIONS; TEMPERATURE; PROBES;
D O I
10.3109/02656730903492916
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
A commercial diagnostic ultrasound scanner (Octoson) was modified for performing hyperthermia treatments. The temperature elevations were induced in tissues by four large, focused ultrasonic transducers whose common focal zone was scanned along a computer controlled path as determined from B-scan images. The system is described and the results of preliminary tests demonstrating some of its capabilities are given. Extensive tests with canine thighs and kidneys were performed. The blood flow to the kidneys was controllable, and thus tumours having different blood perfusion rates could be simulated. The results showed that the system is capable of inducing a local temperature maximum deep in tissues (up to 10 cm was tested) and that tissues with high perfusion rates could be heated.
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页码:1 / 11
页数:11
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