THE HISTONE METHYLTRANSFERASES G9A/GLP REPRESENT NEW PROMISING TARGETS FOR THE TREATMENT OF MULTIPLE MYELOMA

被引：0
|
作者：
De Smedt, E. [1 ]
Devin, J. [2 ]
Liu, H. [3 ]
Maes, A. [1 ]
Maes, K. [1 ]
De Veirman, K. [1 ]
Menu, E. [1 ]
Vanderkerken, K. [1 ]
Moreaux, J. [2 ]
De Bruyne, E. [1 ]
机构：
[1] Vrije Univ Brussel, Dept Hematol & Immunol, Myeloma Ctr Brussels, Brussels, Belgium
[2] CNRS, Inst Human Genet, Lab Monitoring Innovat Therapies, Montpellier, France
[3] Tianjin Med Univ, Dept Hematol, Gen Hosp, Tianjin, Peoples R China
来源：
HAEMATOLOGICA | 2017年 / 102卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
E1211
引用
收藏
页码：497 / 498
页数：2
相关论文
共 50 条
  • [31] Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death
    Yu, H.
    Lin, Q.
    Wang, Y.
    He, Y.
    Fu, S.
    Jiang, H.
    Yu, Y.
    Sun, S.
    Chen, Y.
    Shou, J.
    Li, H.
    CELL DEATH & DISEASE, 2013, 4 : e506 - e506
  • [32] Inhibition of H3K9 methyltransferases G9a/GLP prevents ototoxicity and ongoing hair cell death
    H Yu
    Q Lin
    Y Wang
    Y He
    S Fu
    H Jiang
    Y Yu
    S Sun
    Y Chen
    J Shou
    H Li
    Cell Death & Disease, 2013, 4 : e506 - e506
  • [33] A Subset of the Histone H3 Lysine 9 Methyltransferases Suv39h1, G9a, GLP, and SETDB1 Participate in a Multimeric Complex
    Fritsch, Lauriane
    Robin, Philippe
    Mathieu, Jacques R. R.
    Souidi, Mouloud
    Hinaux, Helene
    Rougeulle, Claire
    Harel-Bellan, Annick
    Ameyar-Zazoua, Maya
    Ait-Si-Ali, Slimane
    MOLECULAR CELL, 2010, 37 (01) : 46 - 56
  • [34] Dual inhibition of EZH2 and G9A/GLP histone methyltransferases by HKMTI-1-005 promotes differentiation of acute myeloid leukemia cells
    Sbirkov, Y.
    Schenk, T.
    Kwok, C.
    Stengel, S.
    Brown, R.
    Brown, G.
    Chesler, L.
    Zelent, A.
    Fuchter, M. J.
    Petrie, K.
    FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY, 2023, 11
  • [35] Unexpected Distinct Roles of the Related Histone H3 Lysine 9 Methyltransferases G9a and G9a-Like Protein in Myoblasts
    Battisti, Valentine
    Pontis, Julien
    Boyarchuk, Ekaterina
    Fritsch, Lauriane
    Robin, Philippe
    Ait-Si-Ali, Slimane
    Joliot, Veronique
    JOURNAL OF MOLECULAR BIOLOGY, 2016, 428 (11) : 2329 - 2343
  • [36] Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice
    Dong-yao Wang
    Joel Kosowan
    James Samsom
    Laura Leung
    Kai-lai Zhang
    Ying-xiang Li
    Yan Xiong
    Jian Jin
    Arturas Petronis
    Gabriel Oh
    Albert H C Wong
    Acta Pharmacologica Sinica, 2018, 39 : 866 - 874
  • [37] Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice
    Wang, Dong-yao
    Kosowan, Joel
    Samsom, James
    Leung, Laura
    Zhang, Kai-lai
    Li, Ying-xiang
    Xiong, Yan
    Jin, Jian
    Petronis, Arturas
    Oh, Gabriel
    Wong, Albert H. C.
    ACTA PHARMACOLOGICA SINICA, 2018, 39 (05) : 866 - 874
  • [38] Distinct Roles for Histone Methyltransferases G9a and GLP in Cancer Germ-Line Antigen Gene Regulation in Human Cancer Cells and Murine Embryonic Stem Cells
    Link, Petra A.
    Gangisetty, Omkaram
    James, Smitha R.
    Woloszynska-Read, Anna
    Tachibana, Makoto
    Shinkai, Yoichi
    Karpf, Adam R.
    MOLECULAR CANCER RESEARCH, 2009, 7 (06) : 851 - 862
  • [39] Histone methyltransferases EHMT1 and EHMT2 (GLP/G9A) maintain PARP inhibitor resistance in high-grade serous ovarian carcinoma
    Zachary L. Watson
    Tomomi M. Yamamoto
    Alexandra McMellen
    Hyunmin Kim
    Connor J. Hughes
    Lindsay J. Wheeler
    Miriam D. Post
    Kian Behbakht
    Benjamin G. Bitler
    Clinical Epigenetics, 2019, 11
  • [40] Histone methyltransferases EHMT1 and EHMT2 (GLP/G9A) maintain PARP inhibitor resistance in high-grade serous ovarian carcinoma
    Watson, Zachary L.
    Yamamoto, Tomomi M.
    McMellen, Alexandra
    Kim, Hyunmin
    Hughes, Connor J.
    Wheeler, Lindsay J.
    Post, Miriam D.
    Behbakht, Kian
    Bitler, Benjamin G.
    CLINICAL EPIGENETICS, 2019, 11 (01)
12345