THE HISTONE METHYLTRANSFERASES G9A/GLP REPRESENT NEW PROMISING TARGETS FOR THE TREATMENT OF MULTIPLE MYELOMA

被引：0
|
作者：
De Smedt, E. [1 ]
Devin, J. [2 ]
Liu, H. [3 ]
Maes, A. [1 ]
Maes, K. [1 ]
De Veirman, K. [1 ]
Menu, E. [1 ]
Vanderkerken, K. [1 ]
Moreaux, J. [2 ]
De Bruyne, E. [1 ]
机构：
[1] Vrije Univ Brussel, Dept Hematol & Immunol, Myeloma Ctr Brussels, Brussels, Belgium
[2] CNRS, Inst Human Genet, Lab Monitoring Innovat Therapies, Montpellier, France
[3] Tianjin Med Univ, Dept Hematol, Gen Hosp, Tianjin, Peoples R China
来源：
HAEMATOLOGICA | 2017年 / 102卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
E1211
引用
收藏
页码：497 / 498
页数：2
相关论文
共 50 条
  • [21] Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage
    Ginjala, Vasudeva
    Rodriguez-Colon, Lizahira
    Ganguly, Bratati
    Gangidi, Prawallika
    Gallina, Paul
    Al-Hraishawi, Husam
    Kulkarni, Atul
    Tang, Jeremy
    Gheeya, Jinesh
    Simhadri, Srilatha
    Yao, Ming
    Xia, Bing
    Ganesan, Shridar
    SCIENTIFIC REPORTS, 2017, 7
  • [22] Protein-lysine methyltransferases G9a and GLP1 promote responses to DNA damage
    Vasudeva Ginjala
    Lizahira Rodriguez-Colon
    Bratati Ganguly
    Prawallika Gangidi
    Paul Gallina
    Husam Al-Hraishawi
    Atul Kulkarni
    Jeremy Tang
    Jinesh Gheeya
    Srilatha Simhadri
    Ming Yao
    Bing Xia
    Shridar Ganesan
    Scientific Reports, 7
  • [23] Histone methyltransferases: a new class of therapeutic targets in cancer treatment?
    Chaib, Hassiba
    Prebet, Thomas
    Vey, Norbert
    Collette, Yves
    M S-MEDECINE SCIENCES, 2011, 27 (8-9): : 725 - 732
  • [24] Protein lysine methyltransferase G9a acts on non-histone targets
    Rathert, Philipp
    Dhayalan, Arunkumar
    Murakami, Marie
    Zhang, Xing
    Tamas, Raluca
    Jurkowska, Renata
    Komatsu, Yasuhiko
    Shinkai, Yoichi
    Cheng, Xiaodong
    Jeltsch, Albert
    NATURE CHEMICAL BIOLOGY, 2008, 4 (06) : 344 - 346
  • [25] Protein lysine methyltransferase G9a acts on non-histone targets
    Philipp Rathert
    Arunkumar Dhayalan
    Marie Murakami
    Xing Zhang
    Raluca Tamas
    Renata Jurkowska
    Yasuhiko Komatsu
    Yoichi Shinkai
    Xiaodong Cheng
    Albert Jeltsch
    Nature Chemical Biology, 2008, 4 : 344 - 346
  • [26] Histone Methyltransferases G9a/Ehmt2 and GLP/Ehmt1 Are Associated with Cell Viability and Poorer Prognosis in Neuroblastoma and Ewing Sarcoma
    Souza, Barbara Kunzler
    Freire, Natalia Hogetop
    Monteiro, Thiago Santos
    Herlinger, Alice Laschuk
    Jaeger, Mariane
    Dalmolin, Matheus G. S.
    de Farias, Caroline Brunetto
    Gregianin, Lauro
    Brunetto, Andre T.
    Brunetto, Algemir L.
    Thiele, Carol J.
    Roesler, Rafael
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (20)
  • [27] De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9a
    Vinson, David A.
    Stephens, Kimberly E.
    O'Meally, Robert N.
    Bhat, Shri
    Dancy, Blair C. R.
    Cole, Robert N.
    Yegnasubramanian, Srinivasan
    Taverna, Sean D.
    EPIGENETICS & CHROMATIN, 2022, 15 (01)
  • [28] De novo methylation of histone H3K23 by the methyltransferases EHMT1/GLP and EHMT2/G9a
    David A. Vinson
    Kimberly E. Stephens
    Robert N. O’Meally
    Shri Bhat
    Blair C. R. Dancy
    Robert N. Cole
    Srinivasan Yegnasubramanian
    Sean D. Taverna
    Epigenetics & Chromatin, 15
  • [29] Promising new treatment for multiple myeloma
    Gourd, Elizabeth
    LANCET ONCOLOGY, 2018, 19 (12): : E673 - E673
  • [30] The Histone Methyltransferase Inhibitor A-366 Uncovers a Role for G9a/GLP in the Epigenetics of Leukemia
    Pappano, William N.
    Guo, Jun
    He, Yupeng
    Ferguson, Debra
    Jagadeeswaran, Sujatha
    Osterling, Donald J.
    Gao, Wenqing
    Spence, Julie K.
    Pliushchev, Marina
    Sweis, Ramzi F.
    Buchanan, Fritz G.
    Michaelides, Michael R.
    Shoemaker, Alexander R.
    Tse, Chris
    Chiang, Gary G.
    PLOS ONE, 2015, 10 (07):
12345