The Application of Dioxygenase-Based Chemoenzymatic Processes to the Total Synthesis of Natural Products

被引:19
|
作者
Lan, Ping [1 ]
Ye, Sebastian [2 ]
Banwell, Martin G. [1 ,2 ]
机构
[1] Jinan Univ, Inst Adv & Appl Chem Synth, Guangzhou 510632, Guangdong, Peoples R China
[2] Australian Natl Univ, Inst Adv Studies, Res Sch Chem, Canberra, ACT 2601, Australia
基金
澳大利亚研究理事会;
关键词
chemoenzymatic; cis-1; 2-dihydrocatechols; cross-couplings; Diels-Alder cycloadditions; photochemical rearrangements; sesquiterpenes; HIGHLY OXYGENATED TROPONOIDS; TAXANE DITERPENE SYNTHESIS; ACID VITAMIN-C; MICROBIAL OXIDATION; ENANTIOSELECTIVE SYNTHESIS; ENANTIODIVERGENT SYNTHESIS; ABSOLUTE-CONFIGURATION; ENANTIOMERICALLY PURE; BIOLOGICAL EVALUATION; CIS-DIHYDROCATECHOLS;
D O I
10.1002/asia.201900988
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This Minireview describes the exploitation of certain enzymatically derived, readily accessible, and enantiomerically pure cis-1,2-dihydrocatechols as starting materials in the chemical synthesis of a range of biologically active natural products, most notably sesquiterpenoids and alkaloids.
引用
收藏
页码:4001 / 4012
页数:12
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