Studies on the enzymatic kinetic resolution of β-hydroxy ketones

被引：24
|
作者：
Joly, S [1 ]
Nair, MS [1 ]
机构：
[1] CSIR, Reg Res Lab, Div Organ Chem, Trivandrum 695019, Kerala, India
来源：
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 2003年 / 22卷 / 3-4期
关键词：
beta-hydroxy ketones; kinetic resolution; Candida cylindracea lipase; enantioselectivity;
D O I：
10.1016/S1381-1177(03)00027-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Kinetic resolution of aldol products using enzymatic transesterification and hydrolysis are described. The effect of structure of aldols on the enantioselectivity have also been studied in detail. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：151 / 160
页数：10
相关论文
共 50 条
  • [41] KINETIC ENZYMATIC RESOLUTION OF BETA-TETRALOLS
    MARTINEZ, GR
    TETRAHEDRON-ASYMMETRY, 1995, 6 (07) : 1491 - 1494
  • [42] Catalytic Non-Enzymatic Kinetic Resolution
    Pellissier, Helene
    ADVANCED SYNTHESIS & CATALYSIS, 2011, 353 (10) : 1613 - 1666
  • [43] A facile preparation of (±)-β-hydroxy nitriles and their enzymatic resolution with lipases
    Kamal, A
    Khanna, GBR
    TETRAHEDRON-ASYMMETRY, 2001, 12 (03) : 405 - 410
  • [44] EVALUATION OF PROCESS OPTIONS FOR ENZYMATIC KINETIC RESOLUTION
    STRAATHOF, AJJ
    RAKELS, JLL
    HEIJNEN, JJ
    ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1992, 672 : 497 - 501
  • [45] RESOLUTION OF KETONES VIA CHIRAL ACETALS - KINETIC APPROACH
    MORI, A
    YAMAMOTO, H
    JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (25): : 5444 - 5446
  • [46] KINETIC RESOLUTION OF RACEMIC KETONES WITH K-GLUCORIDE
    CHO, BT
    PARK, WS
    BULLETIN OF THE KOREAN CHEMICAL SOCIETY, 1989, 10 (06) : 618 - 619
  • [47] The first enzymatic resolution of quaternary α-acetoxy α-substituted cyclic ketones
    Tanyeli, Cihangir
    Akhmedov, Idris M.
    Iyigun, Cigdem
    TETRAHEDRON-ASYMMETRY, 2006, 17 (07) : 1125 - 1128
  • [48] KINETIC STUDIES ON ENZYMATIC FIBRINOGEN CLOTTING
    GRYAZNUK.EA
    BELITSER, VA
    BIOCHEMISTRY-MOSCOW, 1965, 30 (04) : 599 - &
  • [49] Kinetic studies of OH reactions with a series of ketones
    Le Calvé, S
    Hitier, D
    Le Bras, G
    Mellouki, A
    JOURNAL OF PHYSICAL CHEMISTRY A, 1998, 102 (24): : 4579 - 4584
  • [50] Asymmetric synthesis of aliphatic 2-hydroxy ketones by enzymatic carboligation of aldehydes
    de Maria, Pablo Dominguez
    Pohl, Martina
    Gocke, Doerte
    Groeger, Harald
    Trauthwein, Harald
    Stillger, Thomas
    Walter, Lydia
    Mueller, Michael
    EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, 2007, 2007 (18) : 2940 - 2944
12345