Studies on the enzymatic kinetic resolution of β-hydroxy ketones

被引：24
|
作者：
Joly, S [1 ]
Nair, MS [1 ]
机构：
[1] CSIR, Reg Res Lab, Div Organ Chem, Trivandrum 695019, Kerala, India
来源：
JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC | 2003年 / 22卷 / 3-4期
关键词：
beta-hydroxy ketones; kinetic resolution; Candida cylindracea lipase; enantioselectivity;
D O I：
10.1016/S1381-1177(03)00027-4
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Kinetic resolution of aldol products using enzymatic transesterification and hydrolysis are described. The effect of structure of aldols on the enantioselectivity have also been studied in detail. (C) 2003 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：151 / 160
页数：10
相关论文
共 50 条
  • [21] Stereoselective formation of bis(α-hydroxy ketones) via enzymatic carboligation
    Dünnwald, T
    Müller, M
    JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (25): : 8608 - 8612
  • [22] An Enzymatic and Environmentally Friendly Route for the Synthesis of Chiral β-Hydroxy Ketones
    Yildiz, Tulay
    CHEMISTRYSELECT, 2019, 4 (27): : 7927 - 7931
  • [23] Enzymatic Kinetic Resolution by Addition of Oxygen
    Harwood, Lucy A.
    Wong, Luet L.
    Robertson, Jeremy
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2021, 60 (09) : 4434 - 4447
  • [24] Kinetic enzymatic resolution of cyclopropane derivatives
    Pietruszka, J
    Wilhelm, T
    Witt, A
    SYNLETT, 1999, (12) : 1981 - 1983
  • [25] Kinetic enzymatic resolution of cyclopropane derivatives
    Pietruszka, J
    Rieche, ACM
    Wilhelm, T
    Witt, A
    ADVANCED SYNTHESIS & CATALYSIS, 2003, 345 (12) : 1273 - 1286
  • [26] Enzymatic dynamic kinetic resolution of epihalohydrins
    Spelberg, JHL
    Tang, LX
    Kellogg, RM
    Janssen, DB
    TETRAHEDRON-ASYMMETRY, 2004, 15 (07) : 1095 - 1102
  • [27] Enzymatic kinetic resolution of tropic acid
    Klomp, D
    Peters, JA
    Hanefeld, U
    TETRAHEDRON-ASYMMETRY, 2005, 16 (23) : 3892 - 3896
  • [28] Enzymatic Kinetic Resolution of Silybin Diastereoisomers
    Monti, Daniela
    Gazak, Radek
    Marhol, Petr
    Biedermann, David
    Purchartova, Katerina
    Fedrigo, Mirko
    Riva, Sergio
    Kren, Vladimir
    JOURNAL OF NATURAL PRODUCTS, 2010, 73 (04): : 613 - 619
  • [29] Studies in the phenanthrene series III Hydroxy aldehydes and hydroxy ketones
    Mosettig, E
    Burger, A
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1933, 55 : 2981 - 2990
  • [30] KINETIC RESOLUTION OF BICYCLIC KETONES BY ENANTIOSELECTIVE DEPROTONATION
    KIM, HD
    ARCHIVES OF PHARMACAL RESEARCH, 1995, 18 (05) : 369 - 370
12345