Microevolution and independent incursions as main forces shaping H5 Hemagglutinin diversity during a H5N8/H5N5 highly pathogenic avian influenza outbreak in Czech Republic in 2017

被引：5

作者：

Nagy, Alexander ^{[1
]}

Dan, Adam ^{[2
]}

Cernikova, Lenka ^{[1
]}

Vitaskova, Elika ^{[1
]}

Krivda, Vlastimil ^{[1
]}

Hornickova, Jitka ^{[1
]}

Masopust, Roman ^{[1
]}

Sedlak, Kamil ^{[1
]}

机构：

[1] State Vet Inst Prague, Sidlistni 136-24, Prague 16503, Czech Republic

[2] Vet Diagnost Inst, Natl Food Chain Safety Off, Tabornok Utca 2, H-1143 Budapest, Hungary

来源：

ARCHIVES OF VIROLOGY | 2018年 / 163卷 / 08期

关键词：

VIRUSES; POULTRY; NUMBERS;

D O I：

10.1007/s00705-018-3833-7

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Here, we present a comprehensive analysis of the H5N8/H5N5 highly pathogenic avian influenza (HPAI) virus strains detected in the Czech Republic during an outbreak in 2017. Network analysis of the H5 Hemagglutinin (HA) from 99% of the outbreak localities suggested that the diversity of the Czech H5N8/H5N5 viruses was influenced by two basic forces: local microevolution and independent incursions. The geographical occurrence of the central node H5 HA sequences revealed three eco-regions, which apparently played an important role in the origin and further spread of the local H5N8/HPAI variants across the country. A plausible explanation for the observed pattern of diversity is also provided.

引用

页码：2219 / 2224

页数：6

共 50 条

[21] Experimental infection of mandarin duck with highly pathogenic avian influenza A (H5N8 and H5N1) viruses
Kang, Hyun-Mi
Lee, Eun-Kyoung
Song, Byung-Min
Heo, Gyeong-Beom
Jung, Joojin
Jang, Il
Bae, You-Chan
Jung, Suk Chan
Lee, Youn-Jeong
VETERINARY MICROBIOLOGY, 2017, 198 : 59 - 63
[22] Managing the challenges of a highly pathogenic avian influenza H5N8 outbreak in Uganda: a case study
Nantima, N.
Ademun, A. R. O.
Sentumbwe, J.
Ilukor, J.
Kirumira, M. M.
Muwanga, E.
Nakanjako, M. F.
Ndumu, D.
Kiconco, D.
Arinaitwe, E.
Monne, I.
Pavade, G.
Kamata, A.
Von Dobschuetz, S.
REVUE SCIENTIFIQUE ET TECHNIQUE-OFFICE INTERNATIONAL DES EPIZOOTIES, 2019, 38 (01): : 225 - 237
[23] Outbreak of Highly Pathogenic Avian Influenza H5N8 in November 2016 in Wild Birds in Switzerland
Meier, S.
Huessy, D.
Hofmann, M.
Renzullo, S.
Vogler, B. R.
Sigrist, B.
Hoop, R. K.
Albini, S.
SCHWEIZER ARCHIV FUR TIERHEILKUNDE, 2017, 159 (12): : 663 - 667
[24] Genetic Characterization and Zoonotic Potential of Highly Pathogenic Avian Influenza Virus A(H5N6/H5N5), Germany, 2017-2018
Pohlmann, Anne
Hoffmann, Donata
Grund, Christian
Koethe, Susanne
Huessy, Daniela
Meier, Simone M.
King, Jacqueline
Schinkoethe, Jan
Ulrich, Reiner
Harder, Timm
Beer, Martin
EMERGING INFECTIOUS DISEASES, 2019, 25 (10) : 1973 - 1976
[25] Duck production systems and highly pathogenic avian influenza H5N8 in France, 2016–2017
C. Guinat
J. Artois
A. Bronner
J. L. Guérin
M. Gilbert
M. C. Paul
Scientific Reports, 9
[26] Emergence and spread of highly pathogenic avian influenza A(H5N8) in Europe in 2016-2017
Napp, S.
Majo, N.
Sanchez-Gonzalez, R.
Vergara-Alert, J.
TRANSBOUNDARY AND EMERGING DISEASES, 2018, 65 (05) : 1217 - 1226
[27] Avian influenza outbreak in Yorkshire: strain identified as H5N8
不详
VETERINARY RECORD, 2014, 175 (20) : 495 - +
[28] Highly pathogenic avian H5N8 influenza viruses: should we be concerned?
Tate, M. D.
VIRULENCE, 2018, 9 (01) : 20 - 21
[29] Experimental infection of dogs with highly pathogenic avian influenza virus (H5N8)
Yuk, Seong-Su
Lee, Dong-Hun
Park, Jae-Keun
Tseren-Ochir, Erdene-Ochir
Kwon, Jung-Hoon
Noh, Jin-Yong
Song, Chang-Seon
JOURNAL OF VETERINARY SCIENCE, 2017, 18 : 381 - 384
[30] Deaths among Wild Birds during Highly Pathogenic Avian Influenza A(H5N8) Virus Outbreak, the Netherlands
Kleyheeg, Erik
Slaterus, Roy
Bodewes, Rogier
Rijks, Jolianne M.
Spierenburg, Marcel A. H.
Beerens, Nancy
Kelder, Leon
Poen, Marjolein J.
Stegeman, Jan A.
Fouchier, Ron A. M.
Kuiken, Thijs
van der Jeugd, Henk P.
EMERGING INFECTIOUS DISEASES, 2017, 23 (12) : 2050 - 2054

← 1 2 3 4 5 →