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Movement-related potentials in Parkinson's disease
被引:38
|作者:
Georgiev, Dejan
[1
,2
]
Lange, Florian
[3
]
Seer, Caroline
[3
]
Kopp, Bruno
[3
]
Jahanshahi, Marjan
[1
]
机构:
[1] UCL, Inst Neurol, Sobell Dept Motor Neurosci & Movement Disorders, London WC1E 6BT, England
[2] Univ Med Ctr Ljubljana, Dept Neurol, Ljubljana, Slovenia
[3] Hannover Med Sch, Dept Neurol, Hannover, Germany
关键词:
Movement-related potentials;
Bereitschaftspotential;
Contingent Negative Variation;
Lateralized readiness potential;
Parkinson's disease;
CONTINGENT NEGATIVE-VARIATION;
SUBTHALAMIC NUCLEUS STIMULATION;
TRANSCRANIAL MAGNETIC STIMULATION;
EVENT-RELATED POTENTIALS;
CORTICAL POTENTIALS;
VOLUNTARY MOVEMENT;
BASAL GANGLIA;
MOTOR CORTEX;
GLOBUS-PALLIDUS;
CEREBRAL-CORTEX;
D O I:
10.1016/j.clinph.2016.04.004
中图分类号:
R74 [神经病学与精神病学];
学科分类号:
摘要:
To date, many different approaches have been used to study the impairment of motor function in Parkinson's disease (PD). Event-related potentials (ERPs) are averaged amplitude fluctuations of the ongoing EEG activity that are time locked to specific sensory, motor or cognitive events, and as such can be used to study different brain processes with an excellent temporal resolution. Movement-related potentials (MRPs) are ERPs associated with processes of voluntary movement preparation and execution in different paradigms. In this review we concentrate on MRPs in PD. We review studies recording the Bereitschaftspotential, the Contingent Negative Variation, and the lateralized readiness potential in PD to highlight the contributions they have made to further understanding motor deficits in PD. Possible directions for future research are also discussed. (C) 2016 International Federation of Clinical Neurophysiology. Published by Elsevier Ireland Ltd. All rights reserved.
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页码:2509 / 2519
页数:11
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