Movement-related cortical activation in familial Parkinson disease

被引：14
|
作者：
Delval, A.
Defebvre, L.
Labyt, E.
Douay, X.
Bourriez, J. -L.
Waucquiez, N.
Derambure, P.
Destee, A.
机构：
[1] Reg Univ Hosp, Dept Clin Neurophysiol, Lille, France
[2] Reg Univ Hosp, Dept Neurol & Movement Disorders, Lille, France
[3] MENRT, Dept Neurosci, EA 2683, IFR 114, Paris, France
来源：
NEUROLOGY | 2006年 / 67卷 / 06期
关键词：
D O I：
10.1212/01.wnl.0000237528.32932.9a
中图分类号：
R74 [神经病学与精神病学];
学科分类号：
摘要：
We sought to determine whether or not first-degree relatives of patients with familial Parkinson disease (FDRs) present impaired movement-related cortical activity. We studied 10 familial Parkinson disease subjects, 10 FDRs, and 10 controls and analyzed event-related mu desynchronization (ERD) and beta synchronization. Forty percent FDRs presented reduced premovement mu ERD latency, suggesting that premovement cortical activation is impaired in FDRs.
引用
收藏
页码：1086 / 1087
页数：2
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