Blood based biomarkers beyond genomics for lung cancer screening

被引：38

作者：

Hanash, Samir M. ^{[1
]}

Ostrin, Edwin Justin ^{[2
]}

Fahrmann, Johannes F. ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Clin Canc Prevent, Houston, TX 77030 USA

[2] Univ Texas MD Anderson Canc Ctr, Dept Pulm Med, Houston, TX 77030 USA

来源：

TRANSLATIONAL LUNG CANCER RESEARCH | 2018年 / 7卷 / 03期

关键词：

Biomarkers; proteins; metabolites; autoantibodies; RISK PREDICTION MODEL; DOSE COMPUTED-TOMOGRAPHY; SERUM BIOMARKER; EARLY-DIAGNOSIS; PANEL; VALIDATION; PLASMA; ADENOCARCINOMA; IDENTIFICATION; METABOLOMICS;

D O I：

10.21037/tlcr.2018.05.13

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

While there is considerable interest at the present time in the development of so-called liquid biopsy approaches for cancer detection based notably on circulating tumor DNA, there are other types of potential biomarkers that show promise for lung cancer screening and early detection. Here we review approaches and some of the promising markers based on proteomics, metabolomics and the immune response to tumor antigens in the form of autoantibodies.

引用

页码：327 / 335

页数：9

共 50 条

[31] Blood-based tumor biomarkers in lung cancer for detection and treatment
Mamdani, Hirva
Ahmed, Shahid
Armstrong, Samantha
Mok, Tony
Jalal, Shadia I.
TRANSLATIONAL LUNG CANCER RESEARCH, 2017, 6 (06) : 648 - 660
[32] Blood-based biomarkers for lung cancer: Ready for prime time?
Vachani, Anil
JOURNAL OF THORACIC ONCOLOGY, 2016, 11 (02) : S14 - S14
[33] Blood-based biomarkers in lung cancer: prognosis and treatment decisions
Xu-Welliver, Meng
Carbone, David P.
TRANSLATIONAL LUNG CANCER RESEARCH, 2017, 6 (06) : 708 - 712
[34] Blood-Based Biomarkers for Predicting Immunotherapy Benefit in Lung Cancer
Camidge, D. Ross
Schenk, Erin L.
CELL, 2020, 183 (02) : 303 - 304
[35] Lung cancer screening trials: Denmark and beyond
Pedersen, Jesper H.
Petersen, Rene H.
Hansen, Henrik J.
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2012, 144 (03): : S7 - S8
[36] Integrated genomics-based approach to identify new therapeutic targets and cancer biomarkers for lung cancer.
Daigo, Yataro
Takano, Atsushi
Nakamura, Yusuke
JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
[37] Tissue and Blood Biomarkers in Lung Cancer: A Review
Duffy, Michael J.
O'Byrne, Ken
ADVANCES IN CLINICAL CHEMISTRY, VOL 86, 2018, 86 : 1 - 21
[38] Blood immune cell biomarkers in lung cancer
Riemann, D.
Cwikowski, M.
Turzer, S.
Giese, T.
Grallert, M.
Schuette, W.
Seliger, B.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2019, 195 (02): : 179 - 189
[39] MICRORNA BIOMARKERS OF LUNG CANCER IN WHOLE BLOOD
Patnaik, Santosh K.
Yendamuri, Sai
Kannisto, Eric
Vachani, Anil
JOURNAL OF THORACIC ONCOLOGY, 2011, 6 (06) : S670 - S671
[40] Biomarkers in Lung Cancer Screening: Achievements, Promises, and Challenges
Seijo, Luis M.
Peled, Nir
Ajona, Daniel
Boeri, Mattia
Field, John K.
Sozzi, Gabriella
Pio, Ruben
Zulueta, Javier J.
Spira, Avrum
Massion, Pierre P.
Mazzone, Peter J.
Montuenga, Luis M.
JOURNAL OF THORACIC ONCOLOGY, 2019, 14 (03) : 343 - 357

← 1 2 3 4 5 →