Blood based biomarkers beyond genomics for lung cancer screening

被引：38

作者：

Hanash, Samir M. ^{[1
]}

Ostrin, Edwin Justin ^{[2
]}

Fahrmann, Johannes F. ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Clin Canc Prevent, Houston, TX 77030 USA

[2] Univ Texas MD Anderson Canc Ctr, Dept Pulm Med, Houston, TX 77030 USA

来源：

TRANSLATIONAL LUNG CANCER RESEARCH | 2018年 / 7卷 / 03期

关键词：

Biomarkers; proteins; metabolites; autoantibodies; RISK PREDICTION MODEL; DOSE COMPUTED-TOMOGRAPHY; SERUM BIOMARKER; EARLY-DIAGNOSIS; PANEL; VALIDATION; PLASMA; ADENOCARCINOMA; IDENTIFICATION; METABOLOMICS;

D O I：

10.21037/tlcr.2018.05.13

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

While there is considerable interest at the present time in the development of so-called liquid biopsy approaches for cancer detection based notably on circulating tumor DNA, there are other types of potential biomarkers that show promise for lung cancer screening and early detection. Here we review approaches and some of the promising markers based on proteomics, metabolomics and the immune response to tumor antigens in the form of autoantibodies.

引用

页码：327 / 335

页数：9

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