PMA suppresses breast cancer cell proliferation via PKCεmediated P-Rex1 downregulation

被引:0
|
作者
Wong, Chuu-Yun [1 ]
Xie, Yan [1 ]
Abel, Peter [1 ]
Scofield, Margaret [1 ]
Tu, Yaping [1 ]
机构
[1] Creighton Univ, Omaha, NE 68178 USA
来源
FASEB JOURNAL | 2014年 / 28卷 / 01期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1148.5
引用
收藏
页数:1
相关论文
共 50 条
  • [31] Inhibition of PKC/MEK pathway suppresses β1-integrin and mitigates breast cancer cells proliferation
    EL-Ashmawy, Nahla E.
    EL-Zamarany, Enas A.
    Khedr, Naglaa F.
    Selim, Hend M.
    Khedr, Eman G.
    TOXICOLOGY REPORTS, 2021, 8 : 1530 - 1537
  • [32] Membrane translocation of P-Rex1 is mediated by G protein βγ subunits and phosphoinositide 3-kinase
    Barber, Mark A.
    Donald, Sarah
    Thelen, Sylvia
    Anderson, Karen E.
    Thelen, Marcus
    Welch, Heidi C. E.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (41) : 29967 - 29976
  • [33] P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer
    J C Montero
    S Seoane
    A Ocaña
    A Pandiella
    Oncogene, 2011, 30 : 1059 - 1071
  • [34] P-Rex1 Promotes Resistance to VEGF/VEGFR-Targeted Therapy in Prostate Cancer
    Goel, Hira Lal
    Pursell, Bryan
    Shultz, Leonard D.
    Greiner, Dale L.
    Brekken, Rolf A.
    Vander Kooi, Craig W.
    Mercurio, Arthur M.
    CELL REPORTS, 2016, 14 (09): : 2193 - 2208
  • [35] P-Rex1, a Guanine Exchange Factor that Is Overexpressed in Breast Cancer, Is a Convergence Node for ErbB and CXCR4 Signaling
    Hynes, Nancy E.
    Gattelli, Albana
    MOLECULAR CELL, 2011, 41 (01) : 5 - 7
  • [36] Tanshinone IIA suppresses gastric cancer cell proliferation and migration by downregulation of FOXM1
    Yu, Jiao
    Wang, Xiaoxia
    Li, Yuhua
    Tang, Bin
    ONCOLOGY REPORTS, 2017, 37 (03) : 1394 - 1400
  • [37] Downregulation of SOX9 suppresses breast cancer cell proliferation and migration by regulating apoptosis and cell cycle arrest
    Wang, Yu-Feng
    Dang, Hui-Feng
    Luo, Xu
    Wang, Qian-Qian
    Gao, Chen
    Tian, Ying-Xia
    ONCOLOGY LETTERS, 2021, 22 (01)
  • [38] The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer
    Yang, Xue
    Cruz, Miguel I.
    Nguyen, Elizabeth V.
    Huang, Cheng
    Schittenhelm, Ralf B.
    Luu, Jennii
    Cowley, Karla J.
    Shin, Sung-Young
    Nguyen, Lan K.
    Sian, Terry C. C. Lim Kam
    Clark, Kimberley C.
    Simpson, Kaylene J.
    Ma, Xiuquan
    Daly, Roger J.
    ONCOGENE, 2023, 42 (11) : 833 - 847
  • [39] The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer
    Xue Yang
    Miguel I. Cruz
    Elizabeth V. Nguyen
    Cheng Huang
    Ralf B. Schittenhelm
    Jennii Luu
    Karla J. Cowley
    Sung-Young Shin
    Lan K. Nguyen
    Terry C. C. Lim Kam Sian
    Kimberley C. Clark
    Kaylene J. Simpson
    Xiuquan Ma
    Roger J. Daly
    Oncogene, 2023, 42 : 833 - 847
  • [40] Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription
    Riina Kaukonen
    Anja Mai
    Maria Georgiadou
    Markku Saari
    Nicola De Franceschi
    Timo Betz
    Harri Sihto
    Sami Ventelä
    Laura Elo
    Eija Jokitalo
    Jukka Westermarck
    Pirkko-Liisa Kellokumpu-Lehtinen
    Heikki Joensuu
    Reidar Grenman
    Johanna Ivaska
    Nature Communications, 7