PMA suppresses breast cancer cell proliferation via PKCεmediated P-Rex1 downregulation

被引:0
|
作者
Wong, Chuu-Yun [1 ]
Xie, Yan [1 ]
Abel, Peter [1 ]
Scofield, Margaret [1 ]
Tu, Yaping [1 ]
机构
[1] Creighton Univ, Omaha, NE 68178 USA
来源
FASEB JOURNAL | 2014年 / 28卷 / 01期
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
1148.5
引用
收藏
页数:1
相关论文
共 50 条
  • [21] PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer cell migration
    Qin, Jianbing
    Scofield, Margaret A.
    Dowd, Frank J.
    Hoshino, Mikio
    To, Yaping
    FASEB JOURNAL, 2007, 21 (05): : A386 - A386
  • [22] Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation
    Barrio-Real, Laura
    Benedetti, Lorena G.
    Engel, Nora
    Tu, Yaping
    Cho, Soonweng
    Sukumar, Saraswati
    Kazanietz, Marcelo G.
    BREAST CANCER RESEARCH, 2014, 16 (05) : 1 - 13
  • [23] Downregulation of Calbindin 1 by miR-454-3p Suppresses Cell Proliferation in Nonsmall Cell Lung Cancer In Vitro
    Jin, Caijin
    Lin, Tao
    Shan, Liqun
    CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS, 2019, 34 (02) : 119 - 127
  • [24] Macrophages promote cell proliferation in colorectal cancer via IL-1β-mediated downregulation of miR-28-3p
    Fan, H-N
    Liao, X-H
    Zhang, J.
    Zheng, H-M
    JOURNAL OF BIOLOGICAL REGULATORS AND HOMEOSTATIC AGENTS, 2020, 34 (05): : 1657 - 1668
  • [25] Subtype-specific overexpression of the Rac-GEF P-REX1 in breast cancer is associated with promoter hypomethylation
    Laura Barrio-Real
    Lorena G Benedetti
    Nora Engel
    Yaping Tu
    Soonweng Cho
    Saraswati Sukumar
    Marcelo G Kazanietz
    Breast Cancer Research, 16
  • [26] MicroRNA-802 suppresses breast cancer proliferation through downregulation of FoxM1
    Yuan, Feng
    Wang, Wei
    MOLECULAR MEDICINE REPORTS, 2015, 12 (03) : 4647 - 4651
  • [27] Downregulation of Bmi1 in breast cancer stem cells suppresses tumor growth and proliferation
    Srinivasan, Mathangi
    Bharali, Dhruba J.
    Sudha, Thangirala
    Khedr, Maha
    Guest, Ian
    Sell, Stewart
    Glinsky, Gennadi V.
    Mousa, Shaker A.
    ONCOTARGET, 2017, 8 (24) : 38731 - 38742
  • [28] P-Rex1 participates in Neuregulin-ErbB signal transduction and its expression correlates with patient outcome in breast cancer
    Montero, J. C.
    Seoane, S.
    Ocana, A.
    Pandiella, A.
    ONCOGENE, 2011, 30 (09) : 1059 - 1071
  • [29] P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration
    Hernandez-Negrete, Ivette
    Carretero-Ortega, Jorge
    Rosenfeldt, Hans
    Hernandez-Garcia, Ricardo
    Calderon-Salinas, J. Victor
    Reyes-Cruz, Guadalupe
    Gutkind, J. Silvio
    Vazquez-Prado, Jose
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2007, 282 (32) : 23708 - 23715
  • [30] P-REX1 is a novel PTEN-interacting protein that activates PI3K signaling in breast cancer
    Dillon, Lloye M.
    Bean, Jennifer R.
    Balko, Justin M.
    McDonald, W. Hayes
    Friedman, David B.
    Gonzalez-Angulo, Ana M.
    Mills, Gordon B.
    Arteaga, Carlos L.
    Miller, Todd W.
    CANCER RESEARCH, 2013, 73 (08)