Cutaneous and Gastrointestinal Leukocytoclastic Vasculitis Induced by Palbociclib in a Metastatic Breast Cancer Patient: A Case Report

被引：8

作者：

Guillemois, Sylvere ^{[1
]}

Patsouris, Anne ^{[1
]}

Peyraga, Guillaume ^{[2
]}

Chassain, Kevin ^{[3
]}

Le Corre, Yannick ^{[3
]}

Campone, Mario ^{[1
]}

Augereau, Paule ^{[1
]}

机构：

[1] Ctr Paul Papin, Med Oncol Dept, Inst Cancerol Ouest, Angers, France

[2] Ctr Paul Papin, Radiat Therapy Dept, Inst Cancerol Ouest, Angers, France

[3] Univ Hosp Angers, Dermatol Dept, Angers, France

来源：

CLINICAL BREAST CANCER | 2018年 / 18卷 / 05期

关键词：

Cyclin-dependent kinase 4/6 inhibitor; Drug-induced vasculitis; Faslodex; Fulvestrant; Ibrance; Vasculitis treatment; RANDOMIZED CONTROLLED-TRIAL; THERAPY; LETROZOLE;

D O I：

10.1016/j.clbc.2018.07.006

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The efficacy and safety of palbociclib, a cyclindependent kinase 4/6 inhibitor, used in combination with fulvestrant was assessed in women with advanced breast cancer (ABC) whose disease had progressed during previous endocrine therapy, with a significant improvement of progression-free survival and good health-related quality of life. We report a case of an 80-year-old patient with ABC who presented a cutaneous and gastrointestinal vasculitis during treatment with palbociclib and fulvestrant. The skin biopsy was consistent with a leukocytoclastic vasculitis with immunoglobulin A deposits in dermal blood vessels. The symptoms disappeared with the arrest of palbociclib and fulvestrant treatment and a high dose corticotherapy. (C) 2018 Elsevier Inc. All rights reserved.

引用

页码：E755 / E758

页数：4

共 50 条

[21] ThiamazoleANCA-negative cutaneous leukocytoclastic vasculitis: case report
Reactions Weekly, 2022, 1888 (1) : 320 - 320
[22] AmiodaroneCutaneous leukocytoclastic vasculitis in an elderly patient: case report
Reactions Weekly, 2010, 1283 (1) : 10 - 10
[23] TamoxifenNon-purpuric cutaneous leukocytoclastic vasculitis: case report
Reactions Weekly, 2019, 1746 (1) : 190 - 190
[24] OLANZAPINE INDUCED CUTANEOUS LEUKOCYTOCLASTIC VASCULITIS
Karmacharya, Paras
Aryal, Madan R.
Donato, Anthony A.
JOURNAL OF GENERAL INTERNAL MEDICINE, 2013, 28 : S366 - S366
[25] Adalimumab-induced leukocytoclastic vasculitis in a patient with ankylosing spondylitis: A case report
Khabbazi, Alireza
Hajialilo, Mehrzad
Tekantapeh, Sepideh Tahsini
Tabrizi, Sahar Farshchi
Salehi, Alireza
CLINICAL CASE REPORTS, 2024, 12 (08):
[26] ErlotinibCutaneous leukocytoclastic vasculitis in an elderly patient: case report
Reactions Weekly, 2013, 1471 (1) : 23 - 23
[27] Cutaneous leukocytoclastic vasculitis induced by thiamazole
Sato, Ayumi
Takemori, Chihiro
Fukumoto, Takeshi
Aoyama, Nazuki
Tajima, Shoko
Fujiwara, Susumu
Nishigori, Chikako
JOURNAL OF DERMATOLOGY, 2021, 48 (12): : E604 - E605
[28] Nimesulide induced leukocytoclastic vasculitis and hepatitis: a case report
Bhattacharya, Prasanta Kumar
Barman, Bhupen
Roy, Aakash
Jamil, Md
Lyngdoh, Monaliza
Mishra, Jaya
SPRINGERPLUS, 2015, 4
[29] Ceftriaxone-induced leukocytoclastic vasculitis: a case report and literature review of antibiotic-induced leukocytoclastic vasculitis
Almasoudi, Aseel A.
Bablghaith, Eman S.
Alaauldeen, Samaher, I
Falemban, Ayman M.
Sherbeeni, Ahlam A.
Bulkhi, Adeeb A.
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2022, 50 (05)
[30] Metformin-Induced Leukocytoclastic Vasculitis A Case Report
Czarnowicki, Tali
Ramot, Yuval
Ingber, Arieh
Maly, Alexander
Horev, Liran
AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2012, 13 (01) : 61 - 63

← 1 2 3 4 5 →