Cutaneous and Gastrointestinal Leukocytoclastic Vasculitis Induced by Palbociclib in a Metastatic Breast Cancer Patient: A Case Report

被引：8
|
作者：
Guillemois, Sylvere [1 ]
Patsouris, Anne [1 ]
Peyraga, Guillaume [2 ]
Chassain, Kevin [3 ]
Le Corre, Yannick [3 ]
Campone, Mario [1 ]
Augereau, Paule [1 ]
机构：
[1] Ctr Paul Papin, Med Oncol Dept, Inst Cancerol Ouest, Angers, France
[2] Ctr Paul Papin, Radiat Therapy Dept, Inst Cancerol Ouest, Angers, France
[3] Univ Hosp Angers, Dermatol Dept, Angers, France
来源：
CLINICAL BREAST CANCER | 2018年 / 18卷 / 05期
关键词：
Cyclin-dependent kinase 4/6 inhibitor; Drug-induced vasculitis; Faslodex; Fulvestrant; Ibrance; Vasculitis treatment; RANDOMIZED CONTROLLED-TRIAL; THERAPY; LETROZOLE;
D O I：
10.1016/j.clbc.2018.07.006
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
The efficacy and safety of palbociclib, a cyclindependent kinase 4/6 inhibitor, used in combination with fulvestrant was assessed in women with advanced breast cancer (ABC) whose disease had progressed during previous endocrine therapy, with a significant improvement of progression-free survival and good health-related quality of life. We report a case of an 80-year-old patient with ABC who presented a cutaneous and gastrointestinal vasculitis during treatment with palbociclib and fulvestrant. The skin biopsy was consistent with a leukocytoclastic vasculitis with immunoglobulin A deposits in dermal blood vessels. The symptoms disappeared with the arrest of palbociclib and fulvestrant treatment and a high dose corticotherapy. (C) 2018 Elsevier Inc. All rights reserved.
引用
收藏
页码：E755 / E758
页数：4
相关论文
共 50 条
  • [1] Sibutramine (Reductil®)-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
    Ha, You Jin
    Han, You Jin
    Choi, You Won
    Myung, Ki Bum
    Choi, Hae Young
    ANNALS OF DERMATOLOGY, 2011, 23 (04) : 544 - 547
  • [2] Gabapentin-Induced Cutaneous Leukocytoclastic Vasculitis: A Case Report
    Orfao, Ana
    Madeira, Daniela
    Duarte, Daniel Maia
    Pereira, Filipa Galante
    Matos, Clara
    CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (09)
  • [3] Complete response of Palbociclib in metastatic breast cancer patient: A case report
    Payandeh, Mehrdad
    Sadeghi, Edris
    Sadeghi, Masoud
    Aeinfar, Mehrnoush
    Yari, Saba
    BIOMEDICAL RESEARCH AND THERAPY, 2018, 5 (06): : 2365 - 2369
  • [4] PalbociclibCutaneous and GI leukocytoclastic vasculitis (first report with palbociclib): case report
    Reactions Weekly, 2018, 1725 (1) : 236 - 236
  • [5] Unusual cutaneous leukocytoclastic vasculitis: A case report
    Cristea, I. T.
    Sandru, F.
    Spinu, D.
    Goanta, A.
    Popa, A.
    Beiu, C.
    Bosoteanu, L.
    Cizmas, L.
    Paran, A.
    Giurcaneanu, C.
    JOURNAL OF INVESTIGATIVE DERMATOLOGY, 2022, 142 (12) : S192 - S192
  • [6] Nafcillin Implicated in A Case of Cutaneous and Gastrointestinal Leukocytoclastic Vasculitis
    Changqing Xie
    Pancholi, Suchita S.
    Armistead, Niti
    JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2015, 9 (04) : OD6 - OD7
  • [7] NafcillinCutaneous and gastrointestinal leukocytoclastic vasculitis: case report
    Reactions Weekly, 2015, 1550 (1) : 159 - 159
  • [8] Amiodarone-induced cutaneous leukocytoclastic vasculitis: a case report and a review of the literature
    Tumay Ak
    Rumeysa Nur Algan
    Senay Agirgol
    Seyhan Ozakkayunlu Hascicek
    Zafer Turkoglu
    Clinical Rheumatology, 2022, 41 : 2875 - 2881
  • [9] Amiodarone-induced cutaneous leukocytoclastic vasculitis: a case report and a review of the literature
    Ak, Tumay
    Algan, Rumeysa Nur
    Agirgol, Senay
    Hascicek, Seyhan Ozakkayunlu
    Turkoglu, Zafer
    CLINICAL RHEUMATOLOGY, 2022, 41 (09) : 2875 - 2881
  • [10] Cutaneous leukocytoclastic vasculitis in a patient with HIV
    Hodes, S. A.
    Carlson, M.
    JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 119 (01) : S204 - S204
12345