Novel intramolecular aza-Diels-Alder reaction: a facile synthesis of trans-fused 5H-chromeno[2,3-c]acridine derivatives

被引：18

作者：

Reddy, B. V. Subba ^{[1
]}

Antony, Aneesh ^{[1
]}

Yadav, J. S. ^{[1
]}

机构：

[1] Indian Inst Chem Technol, Discovery Lab, Div Organ Chem 1, Hyderabad 500007, Andhra Pradesh, India

来源：

TETRAHEDRON LETTERS | 2010年 / 51卷 / 23期

关键词：

Intramolecular cycloaddition; Alkene-tethered chromene-3-aldehyde; Lewis acid; Chromenoacridines; POTASSIUM CHANNEL OPENERS; ANTIHYPERTENSIVE ACTIVITY;

D O I：

10.1016/j.tetlet.2010.04.018

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel series of 5H-chromeno[2,3-c]acridine derivatives has been prepared through the intramolecular aza-Diels-Alder reaction of alkene-tethered chromene-3-carboxaldehyde with various aromatic amines. This is the first example of the preparation of pentacyclic poly aromatic compounds in a single-step operation at ambient temperature. (C) 2010 Elsevier Ltd. All rights reserved.

引用

页码：3071 / 3074

页数：4

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