Novel intramolecular aza-Diels-Alder reaction: a facile synthesis of trans-fused 5H-chromeno[2,3-c]acridine derivatives

被引：18
|
作者：
Reddy, B. V. Subba [1 ]
Antony, Aneesh [1 ]
Yadav, J. S. [1 ]
机构：
[1] Indian Inst Chem Technol, Discovery Lab, Div Organ Chem 1, Hyderabad 500007, Andhra Pradesh, India
来源：
TETRAHEDRON LETTERS | 2010年 / 51卷 / 23期
关键词：
Intramolecular cycloaddition; Alkene-tethered chromene-3-aldehyde; Lewis acid; Chromenoacridines; POTASSIUM CHANNEL OPENERS; ANTIHYPERTENSIVE ACTIVITY;
D O I：
10.1016/j.tetlet.2010.04.018
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A novel series of 5H-chromeno[2,3-c]acridine derivatives has been prepared through the intramolecular aza-Diels-Alder reaction of alkene-tethered chromene-3-carboxaldehyde with various aromatic amines. This is the first example of the preparation of pentacyclic poly aromatic compounds in a single-step operation at ambient temperature. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3071 / 3074
页数：4
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