Total Synthesis of Auripyrones A and B and Determination of the Absolute Configuration of Auripyrone B

被引：19

作者：

Hayakawa, Ichiro ^{[1
]}

Takemura, Takuma ^{[1
]}

Fukasawa, Emi ^{[1
]}

Ebihara, Yuta ^{[1
]}

Sato, Natsuki ^{[1
]}

Nakamura, Takayasu ^{[1
]}

Suenaga, Kiyotake ^{[1
]}

Kigoshi, Hideo ^{[1
]}

机构：

[1] Univ Tsukuba, Dept Chem, Grad Sch Pure & Appl Sci, Tsukuba, Ibaraki 3058571, Japan

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 13期

关键词：

aldol reactions; auripyrones; diastereoselectiyity; natural products; total synthesis; NATURAL-PRODUCTS; ALDOL REACTIONS; METABOLITES;

D O I：

10.1002/anie.200906662

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

(Figure Presented) The winner takes it aldol: The total synthesis of auripyrones A and B was achieved using a diastereoselective aldol-type reaction with 2, 6-diethyl-3, 5-dimethyl-4-pyrone as a key step. The stereostructure and absolute configura-tion of auripyrone B has also been determined. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA.

引用

页码：2401 / 2405

页数：5

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