Structural and dynamic properties of four-way helical junctions in DNA molecules

被引：0

作者：

Lilley, DMJ ^{[1
]}

机构：

[1] Univ Dundee, Dept Biochem, Canc Res UK Nucle Acid Struct Res Grp, Dundee DD1 5EH, Scotland

来源：

NUCLEIC ACIDS: CURVATURE AND DEFORMATION: RECENT ADVANCES AND NEW PARADIGMS | 2004年 / 884卷

关键词：

D O I：

暂无

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four-way helical junctions in DNA are the central intermediates in genetic recombination. In the presence of divalent metal ions they fold into the stacked X-structure by the pairwise coaxial stacking of helical arms. Exchange between alternative stacking conformers occurs in solution. The structure of four-way junctions is specifically recognised by proteins, notably by the resolving enzymes.

引用

页码：145 / 164

页数：20

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