Bioactive compounds from the endophytic fungus Fusarium proliferatum

被引:27
|
作者
Dame, Zerihun T. [1 ]
Silima, Beauty [2 ]
Gryzenhout, Marieka [3 ]
van Ree, Teunis [2 ]
机构
[1] Univ Gottingen, Dept Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany
[2] Univ Venda, Dept Chem, P Bag X5050, ZA-0950 Thohoyandou, South Africa
[3] Univ Orange Free State, Dept Plant Sci, POB 339, ZA-9300 Bloemfontein, South Africa
关键词
Endophytic fungus; Syzygium cordatum; Fusarium proliferatum; naphthoquinone; NAPHTHOQUINONES; ERGOSTEROL;
D O I
10.1080/14786419.2015.1053089
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The crude extract of an endophytic fungus isolated from Syzygium cordatum and identified as Fusarium proliferatum showed 100% cytotoxicity against the brine shrimp Artemia salina at 100g/mL. Seven coloured, biologically active metabolites - including ergosta-5,7,22-trien-3-ol, nectriafurone-8-methyl ether, 9-O-methyl fusarubin, bostrycoidin, bostrycoidin-9-methyl ether and 8-hydroxy-5,6-dimethoxy-2-methyl-3-(2-oxo-propyl)-1,4-naphthoquinone- were isolated from the extract.
引用
收藏
页码:1301 / 1304
页数:4
相关论文
共 50 条
  • [31] Bioactive sorbicillinoid derivatives from an endophytic fungus Trichoderma citrinoviride
    Xia, Yan-Ping
    Xie, Yan
    Rao, Li
    Yin, Guo-Ping
    FRONTIERS IN MICROBIOLOGY, 2025, 16
  • [32] Bioactive Alkaloids from the Plant Endophytic Fungus Aspergillus terreus
    Ge, Hui Ming
    Peng, Hui
    Guo, Zhi Kai
    Cui, Jiang Tao
    Song, Yong Chun
    Tan, Ren Xiang
    PLANTA MEDICA, 2010, 76 (08) : 822 - 824
  • [33] Two novel aliphatic unsaturated alcohols isolated from a pathogenic fungus Fusarium proliferatum
    Lu, Wanying
    Zhu, Guoliang
    Yuan, Weize
    Han, Zhaoxi
    Dai, Huanqin
    Basiony, Mostafa
    Zhang, Lixin
    Liu, Xueting
    Hsiang, Tom
    Zhang, Jingyu
    SYNTHETIC AND SYSTEMS BIOTECHNOLOGY, 2021, 6 (04) : 446 - 451
  • [34] Preinoculation with Endophytic fungus Phomopsis liquidambaris reduced rice bakanae disease caused by Fusarium proliferatum via enhanced plant resistance
    Zhu, Qiang
    Wu, Yi-Bo
    Chen, Man
    Lu, Fan
    Sun, Kai
    Tang, Meng-Jun
    Zhang, Wei
    Bu, Yuan-Qing
    Dai, Chuan-Chao
    JOURNAL OF APPLIED MICROBIOLOGY, 2022, 133 (03) : 1566 - 1580
  • [35] Sesterterpenes and 2H-Pyran-2-ones (=α-Pyrones) from the Mangrove-Derived Endophytic Fungus Fusarium proliferatum MA-84
    Liu, Dong
    Li, Xiao-Ming
    Li, Chun-Shun
    Wang, Bin-Gui
    HELVETICA CHIMICA ACTA, 2013, 96 (03) : 437 - 444
  • [36] Fusarium proliferatum, an endophytic fungus from Dysoxylum binectariferum Hook.f, produces rohitukine, a chromane alkaloid possessing anti-cancer activity
    Patel Mohana Kumara
    Sebastian Zuehlke
    Vaidyanathan Priti
    Bheemanahally Thimmappa Ramesha
    Singh Shweta
    Gudasalamani Ravikanth
    Ramesh Vasudeva
    Thankayyan Retnabai Santhoshkumar
    Michael Spiteller
    Ramanan Uma Shaanker
    Antonie van Leeuwenhoek, 2012, 101 : 323 - 329
  • [37] Fusarium proliferatum, an endophytic fungus from Dysoxylum binectariferum Hook.f, produces rohitukine, a chromane alkaloid possessing anti-cancer activity
    Kumara, Patel Mohana
    Zuehlke, Sebastian
    Priti, Vaidyanathan
    Ramesha, Bheemanahally Thimmappa
    Shweta, Singh
    Ravikanth, Gudasalamani
    Vasudeva, Ramesh
    Santhoshkumar, Thankayyan Retnabai
    Spiteller, Michael
    Shaanker, Ramanan Uma
    ANTONIE VAN LEEUWENHOEK INTERNATIONAL JOURNAL OF GENERAL AND MOLECULAR MICROBIOLOGY, 2012, 101 (02): : 323 - 329
  • [38] Sesquiterpenoids from Fusarium sp., an Endophytic Fungus in Agriminia pilosa
    Shan, Wei-Guang
    Chen, Xiao-Xiao
    Ying, You-Min
    Zhan, Zha-Jun
    HELVETICA CHIMICA ACTA, 2011, 94 (07) : 1254 - 1259
  • [39] Secondary Metabolites from the Endophytic Fungus Fusarium equiseti and Their Antibacterial Activities
    Liu, Xiao-Bo
    Zheng, Na
    Liang, Li-Qi
    Zhao, Dong-Min
    Qin, Yu-Yue
    Li, Jun
    Yang, Rui-Yun
    CHEMISTRY OF NATURAL COMPOUNDS, 2019, 55 (06) : 1141 - 1144
  • [40] Antibacterial Polyketides from the Plant Endophytic Fungus Fusarium sp.
    Wang, Ru
    Shi, Ying
    Liu, Qianqian
    Sun, Liyan
    Liu, Ling
    NATURAL PRODUCTS JOURNAL, 2024, 14 (08): : 33 - 38