Bioactive compounds from the endophytic fungus Fusarium proliferatum

被引:27
|
作者
Dame, Zerihun T. [1 ]
Silima, Beauty [2 ]
Gryzenhout, Marieka [3 ]
van Ree, Teunis [2 ]
机构
[1] Univ Gottingen, Dept Organ & Biomol Chem, Tammannstr 2, D-37077 Gottingen, Germany
[2] Univ Venda, Dept Chem, P Bag X5050, ZA-0950 Thohoyandou, South Africa
[3] Univ Orange Free State, Dept Plant Sci, POB 339, ZA-9300 Bloemfontein, South Africa
关键词
Endophytic fungus; Syzygium cordatum; Fusarium proliferatum; naphthoquinone; NAPHTHOQUINONES; ERGOSTEROL;
D O I
10.1080/14786419.2015.1053089
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
The crude extract of an endophytic fungus isolated from Syzygium cordatum and identified as Fusarium proliferatum showed 100% cytotoxicity against the brine shrimp Artemia salina at 100g/mL. Seven coloured, biologically active metabolites - including ergosta-5,7,22-trien-3-ol, nectriafurone-8-methyl ether, 9-O-methyl fusarubin, bostrycoidin, bostrycoidin-9-methyl ether and 8-hydroxy-5,6-dimethoxy-2-methyl-3-(2-oxo-propyl)-1,4-naphthoquinone- were isolated from the extract.
引用
收藏
页码:1301 / 1304
页数:4
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