Caspase-9 can be activated in the absence of APAF-1 and bcl-2 provides clonal protection from growth-factor withdrawal induced apoptosis independent of APAF1 and Caspase-9

被引:0
|
作者
Ekert, PG
Read, S
Hawkins, CJ
Marsden, V
Silke, J
Kumar, S
Vaux, DL
机构
[1] Murdoch Childrens Res Inst, Melbourne, Vic, Australia
[2] Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, Australia
[3] Hanson Ctr Canc Res, Adelaide, SA, Australia
关键词
D O I
暂无
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
1575
引用
收藏
页码:276A / 276A
页数:1
相关论文
共 50 条
  • [31] The role of Apaf-1, caspase-9, and bid proteins in etoposide- or paclitaxel-induced mitochondrial events during apoptosis
    Perkins, CL
    Fang, GF
    Kim, CN
    Bhalla, KN
    CANCER RESEARCH, 2000, 60 (06) : 1645 - 1653
  • [32] Expression of caspase-8, caspase-9, APAF-1, XAIP, and survivin in stage II/III colon carcinoma
    Strater, J.
    Herter, I
    Stoltz, J.
    Merkel, G.
    Hinz, U.
    Weitz, J.
    Moller, P.
    ANNALS OF ONCOLOGY, 2008, 19 : 84 - 84
  • [33] Expression and activity of Apaf1 and caspase-9 in granulosa cells during follicular atresia in pig ovaries
    Matsui, T
    Manabe, N
    Goto, Y
    Inoue, N
    Nishihara, S
    Miyamoto, H
    REPRODUCTION, 2003, 126 (01) : 113 - 120
  • [34] Transduction of Apaf-1 or caspase-9 induces apoptosis in A-172 cells that are resistant to p53-mediated apoptosis
    Shinoura, N
    Sakurai, S
    Asai, A
    Kirino, T
    Hamada, H
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2000, 272 (03) : 667 - 673
  • [35] Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas
    Shinoura, N
    Sakurai, S
    Shibasaki, F
    Asai, A
    Kirino, T
    Hamada, H
    BRITISH JOURNAL OF CANCER, 2002, 86 (04) : 587 - 595
  • [36] 染锰大鼠睾丸Caspase-9,Smac,Apaf-1和XIAP的表达
    郭海
    宋爽
    才秀莲
    解剖科学进展, 2017, 23 (06) : 598 - 601
  • [37] Co-transduction of Apaf-1 and caspase-9 highly enhances p53-mediated apoptosis in gliomas
    N Shinoura
    S Sakurai
    F Shibasaki
    A Asai
    T Kirino
    H Hamada
    British Journal of Cancer, 2002, 86 : 587 - 595
  • [38] Apaf-1 and caspase-9 accelerate apoptosis, but do not determine whether factor-deprived or drug-treated cells die
    Ekert, PG
    Read, SH
    Silke, J
    Marsden, VS
    Kaufmann, H
    Hawkins, CJ
    Gerl, R
    Kumar, S
    Vaux, DL
    JOURNAL OF CELL BIOLOGY, 2004, 165 (06): : 835 - 842
  • [39] Alteration of Apoptosis-Related Proteins (Apaf-1, Caspase-9, Bcl-2, p53, and Survivin) According to Malignant Progression in Cutaneous Melanocytic Lesions
    Kang, Yeo-Ju
    Jung, Ji-Han
    Yim, Kwnag Il
    Lee, Kyo-Young
    Lee, Youn Soo
    Kang, Seok Jin
    Kang, Chang Suk
    Kim, Si Yong
    KOREAN JOURNAL OF PATHOLOGY, 2011, 45 (03) : 247 - 253
  • [40] Solution structure of Apaf-1 CARD and its interaction with caspase-9 CARD: A structural basis for specific adaptor/caspase interaction
    Zhou, P
    Chou, J
    Olea, RS
    Yuan, JY
    Wagner, G
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (20) : 11265 - 11270