Caspase-9 can be activated in the absence of APAF-1 and bcl-2 provides clonal protection from growth-factor withdrawal induced apoptosis independent of APAF1 and Caspase-9

被引：0
|
作者：
Ekert, PG
Read, S
Hawkins, CJ
Marsden, V
Silke, J
Kumar, S
Vaux, DL
机构：
[1] Murdoch Childrens Res Inst, Melbourne, Vic, Australia
[2] Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, Australia
[3] Hanson Ctr Canc Res, Adelaide, SA, Australia
来源：
PEDIATRIC RESEARCH | 2003年 / 53卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
1575
引用
收藏
页码：276A / 276A
页数：1
相关论文
共 50 条
  • [21] Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9
    L A O'Reilly
    P Ekert
    N Harvey
    V Marsden
    L Cullen
    D L Vaux
    G Hacker
    C Magnusson
    M Pakusch
    F Cecconi
    K Kuida
    A Strasser
    D C S Huang
    S Kumar
    Cell Death & Differentiation, 2002, 9 : 832 - 841
  • [22] Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis
    Hongjie Wang
    Juan Zhu
    Liping Jiang
    Boying Shan
    Peihan Xiao
    Jiayi Ai
    Na Li
    Feng Qi
    Siyun Niu
    BMC Complementary Medicine and Therapies, 20
  • [23] Apaf-1, Bcl-xL, cytochrome c, and caspase-9 form the critical elements for cerebral vascular protection by erythropoietin
    Chong, ZZ
    Kang, JQ
    Maiese, K
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2003, 23 (03): : 320 - 330
  • [24] Mechanism of Heshouwuyin inhibiting the Cyt c/Apaf-1/Caspase-9/Caspase-3 pathway in spermatogenic cell apoptosis
    Wang, Hongjie
    Zhu, Juan
    Jiang, Liping
    Shan, Boying
    Xiao, Peihan
    Ai, Jiayi
    Li, Na
    Qi, Feng
    Niu, Siyun
    BMC COMPLEMENTARY MEDICINE AND THERAPIES, 2020, 20 (01) : 180
  • [25] Expression and prognostic significance of APAF-1, caspase-8 and caspase-9 in stage II/III colon carcinoma: caspase-8 and caspase-9 is associated with poor prognosis
    Straeter, Joern
    Herter, Ines
    Merkel, Gaby
    Hinz, Ulf
    Weitz, Juergen
    Moeller, Peter
    INTERNATIONAL JOURNAL OF CANCER, 2010, 127 (04) : 873 - 880
  • [26] The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities
    Chu-Chiao Wu
    Sunhee Lee
    Srinivas Malladi
    Miao-Der Chen
    Nicholas J. Mastrandrea
    Zhiwen Zhang
    Shawn B. Bratton
    Nature Communications, 7
  • [27] Apaf-1、Caspase-9及凋亡体调节的研究进展
    孙军培
    刘久华
    中华全科医学, 2013, 11 (07) : 1102 - 1104
  • [28] Structural Insights into DD-Fold Assembly and Caspase-9 Activation by the Apaf-1 Apoptosome
    Su, Tsung-Wei
    Yang, Chao-Yu
    Kao, Wen-Pin
    Kuo, Bai-Jiun
    Lin, Shan-Meng
    Lin, Jung-Yaw
    Lo, Yu-Chih
    Lin, Su-Chang
    STRUCTURE, 2017, 25 (03) : 407 - 420
  • [29] The Apaf-1 apoptosome induces formation of caspase-9 homo- and heterodimers with distinct activities
    Wu, Chu-Chiao
    Lee, Sunhee
    Malladi, Srinivas
    Chen, Miao-Der
    Mastrandrea, Nicholas J.
    Zhang, Zhiwen
    Bratton, Shawn B.
    NATURE COMMUNICATIONS, 2016, 7
  • [30] Nitric oxide donors inhibit formation of the Apaf-1/caspase-9 apoptosome and activation of caspases
    Zech, B
    Köhl, R
    von Knethen, A
    Brüne, B
    BIOCHEMICAL JOURNAL, 2003, 371 : 1055 - 1064
12345