Caspase-9 can be activated in the absence of APAF-1 and bcl-2 provides clonal protection from growth-factor withdrawal induced apoptosis independent of APAF1 and Caspase-9

被引：0
|
作者：
Ekert, PG
Read, S
Hawkins, CJ
Marsden, V
Silke, J
Kumar, S
Vaux, DL
机构：
[1] Murdoch Childrens Res Inst, Melbourne, Vic, Australia
[2] Walter & Eliza Hall Inst Med Res, Melbourne, Vic 3050, Australia
[3] Hanson Ctr Canc Res, Adelaide, SA, Australia
来源：
PEDIATRIC RESEARCH | 2003年 / 53卷 / 04期
关键词：
D O I：
暂无
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
1575
引用
收藏
页码：276A / 276A
页数：1
相关论文
共 50 条
  • [1] Oligomerization and activation of caspase-9, induced by Apaf-1 CARD
    Shiozaki, EN
    Chai, JJ
    Shi, Y
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (07) : 4197 - 4202
  • [2] Caspase-9 and APAF-1 form an active holoenzyme
    Rodriguez, J
    Lazebnik, Y
    GENES & DEVELOPMENT, 1999, 13 (24) : 3179 - 3184
  • [3] Caspase-9, Bcl-XL, and Apaf-1 form a ternary complex
    Pan, GH
    O'Rourke, K
    Dixit, VM
    JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (10) : 5841 - 5845
  • [4] An epistatic effect of apaf-1 and caspase-9 on chlamydial infection
    Mohd. Akhlakur Rahman
    Mutsunori Shirai
    Md. Abdul Aziz
    Rie Ushirokita
    Sayuri Kubota
    Harumi Suzuki
    Yoshinao Azuma
    Apoptosis, 2015, 20 : 1271 - 1280
  • [5] Molecular determinants of caspase-9 activation by the Apaf-1 apoptosome
    Hu, Qi
    Wu, Di
    Chen, Wen
    Yan, Zhen
    Yan, Chuangye
    He, Tianxi
    Liang, Qionglin
    Shi, Yigong
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (46) : 16254 - 16261
  • [6] Taurine inhibits apoptosis by preventing formation of the Apaf-1/caspase-9 apoptosome
    Takatani, T
    Takahashi, K
    Uozumi, Y
    Shikata, E
    Yamamoto, Y
    Ito, T
    Matsuda, T
    Schaffer, SW
    Fujio, Y
    Azuma, J
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2004, 287 (04): : C949 - C953
  • [7] Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation
    Hu, YM
    Benedict, MA
    Wu, DY
    Inohara, N
    Núñez, G
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1998, 95 (08) : 4386 - 4391
  • [8] An epistatic effect of apaf-1 and caspase-9 on chlamydial infection
    Rahman, Mohd. Akhlakur
    Shirai, Mutsunori
    Aziz, Md. Abdul
    Ushirokita, Rie
    Kubota, Sayuri
    Suzuki, Harumi
    Azuma, Yoshinao
    APOPTOSIS, 2015, 20 (10) : 1271 - 1280
  • [9] Regulation of the Apaf-1/Caspase-9 apoptosome by caspase-3 and XIAP
    Zou, H
    Yang, RM
    Hao, JS
    Wang, J
    Sun, CH
    Fesik, SW
    Wu, JC
    Tomaselli, KJ
    Armstrong, RC
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2003, 278 (10) : 8091 - 8098
  • [10] Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome
    Marsden, VS
    O'Connor, L
    O'Reilly, LA
    Silke, J
    Metcalf, D
    Ekert, PG
    Huang, DCS
    Cecconi, F
    Kuida, K
    Tomaselli, KJ
    Roy, S
    Nicholson, DW
    Vaux, DL
    Bouillet, P
    Adams, JM
    Strasser, A
    NATURE, 2002, 419 (6907) : 634 - 637
12345