Synthesis of some novel 2,3,4,8,9-pentahydro-7-(4-haloaryl)pyrazolo[5,1-e]benzo[1,5]oxazocines and 2,3(erythro),7,8-tetrahydro-2-aryl-3-(4-fluoro-3-methylbenzoyl)-6-(4-haloaryl)pyrazolo[5,1-d]benzo[1,4]oxazepines via solid-liquid PTC

In this communication, a simple and straightforward procedure for the heterocyclization of 1H-4,5-dihydro-3-(4-haloaryl)-5-substituted phenylpyrazoles (4) with 1-bromo-3-chloropropane and 2,3-dibromo-1-(4-fluoro-3-methylphenyl)-3-phenylpropanone affording 2,3,4,8,9-pentahydro-7-(4-haloaryl)pyrazolo[5,1-e]benzo[1,5] oxazocines 5 and regioselective synthesis of 2,3(erythro),7,8-tetrahydro-2aryl-3-(4-fluoro-3-methylbenzoyl)-6-(4-halophenyl)pyrazolo[5,1-d]benzo[1,4]oxa- zepines 6, respectively, via solid-liquid PTC is reported. All the synthesized compounds have been characterized on the basis of their spectral studies (IR, PMR, and MS) and analytical data.