Analysis of haemodynamic factors involved in carotid atherosclerosis using computational fluid dynamics

被引：25

作者：

Martin, D. ^{[1
]}

Zaman, A. ^{[2
]}

Hacker, J. ^{[4
]}

Mendelow, D. ^{[3
]}

Birchall, D. ^{[1
]}

机构：

[1] Newcastle Reg Neurosci Ctr, Dept Neuroradiol, Newcastle Upon Tyne, Tyne & Wear, England

[2] Newcastle Reg Cardiothorac Ctr, Newcastle Upon Tyne, Tyne & Wear, England

[3] Newcastle Reg Neurosci Ctr, Dept Neurosurg, Newcastle Upon Tyne, Tyne & Wear, England

[4] Arup Fluid Dynam Grp, London, England

来源：

BRITISH JOURNAL OF RADIOLOGY | 2009年 / 82卷

关键词：

VASCULAR ENDOTHELIAL-CELLS; WALL SHEAR-STRESS; NITRIC-OXIDE SYNTHASE; BLOOD-FLOW; IN-VIVO; SUPEROXIDE-DISMUTASE; ARTERY BIFURCATION; MECHANICAL-STRESS; GENE-EXPRESSION; YOUNG-ADULTS;

D O I：

10.1259/bjr/59367266

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Atherosclerosis presents a massive healthcare burden in both the developing and developed world. There is mounting evidence relating to the involvement of haemodynamic factors in the pathogenesis of this process. This article aims to review the current understandings that have developed in this area, and to present a demonstrative case study obtained using state of the art computational fluid dynamics (CFD) methodology to model and analyse haemodynamic factors within the atheromatous carotid artery bifurcation.

引用

页码：S33 / S38

页数：6

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