Acellular pertussis vaccines and complement killing of Bordetella pertussis

被引：25
|
作者：
Weiss, AA
Patton, AK
Millen, SH
Chang, SJ
Ward, JI
Bernstein, DI
机构：
[1] Univ Cincinnati, Dept Mol Genet Biochem & Microbiol, Cincinnati, OH 45267 USA
[2] Univ Calif Los Angeles, Harbor UCLA Med Ctr, Ctr Vaccine Res, Torrance, CA 90509 USA
[3] Cincinnati Childrens Hosp Med Ctr, Div Infect Dis, Cincinnati, OH USA
来源：
INFECTION AND IMMUNITY | 2004年 / 72卷 / 12期
关键词：
D O I：
10.1128/IAI.72.12.7346-7351.2004
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Antibody-dependent complement killing of Bordetella pertussis after immunization with a three-component acellular pertussis vaccine was characterized. Postimmunization activity was unchanged for about half of the adult vaccine recipients. The responses of the other individuals were complex, with evidence of both beneficial and antagonistic responses occurring, sometimes in the same individual.
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页码：7346 / 7351
页数：6
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