Model systems for the CO-releasing flavonol 2,4-dioxygenase enzyme

被引:56
|
作者
Pap, Jozsef Sandor [1 ]
Kaizer, Jozsef [1 ]
Speier, Gabor [1 ]
机构
[1] Univ Pannonia, Dept Chem, H-8201 Veszprem, Hungary
关键词
Bioinorganic chemistry; CO-releasing dioxygenases; Flavonol; Copper; Biomimetic oxygenation; DEPENDENT QUERCETIN 2,3-DIOXYGENASE; CRYSTAL-STRUCTURE; ASPERGILLUS-FLAVUS; O-BS; STOICHIOMETRIC OXYGENATION; CATALYZED OXYGENATION; FUNCTIONAL-ANALYSIS; MECHANISM; COPPER; COMPLEXES;
D O I
10.1016/j.ccr.2009.11.009
中图分类号
O61 [无机化学];
学科分类号
070301 ; 081704 ;
摘要
In this review structural and reactivity studies on the co-ligand containing model complexes for the flavonol 2,4-dioxygenase (FDO) are covered. The main focus is on the relationship between the structural features of the copper-containing model complexes, and their activity in the enzyme-like reactions. Some radical initiated reactions and catalytic systems will also be discussed. (C) 2009 Elsevier B.V. All rights reserved.
引用
收藏
页码:781 / 793
页数:13
相关论文
共 50 条
  • [41] Stability, unfolding, and structural changes of cofactor-free 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase
    Beermann, Bernd
    Guddorf, Jessica
    Boehm, Kristian
    Albers, Alexander
    Kolkenbrock, Stephan
    Fetzner, Susanne
    Hinz, H. -J.
    BIOCHEMISTRY, 2007, 46 (14) : 4241 - 4249
  • [42] Design, Synthesis, and Functional Evaluation of CO-Releasing Molecules Triggered by Penicillin G Amidase as a Model Protease
    Sitnikov, Nikolay S.
    Li, Yingchun
    Zhang, Danfeng
    Yard, Benito
    Schmalz, Hans-Guenther
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2015, 54 (42) : 12314 - 12318
  • [43] Iron Dienylphosphate Tricarbonyl Complexes as Water-Soluble Enzyme-Triggered CO-Releasing Molecules (ET-CORMs)
    Romanski, Steffen
    Ruecker, Hannelore
    Stamellou, Eleni
    Guttentag, Miguel
    Neudoerfl, Joerg-Martin
    Alberto, Roger
    Amslinger, Sabine
    Yard, Benito
    Schmalz, Hans-Guenther
    ORGANOMETALLICS, 2012, 31 (16) : 5800 - 5809
  • [44] Mononuclear nickel(ii)-flavonolate complexes of tetradentate tripodal 4N ligands as structural and functional models for quercetin 2,4-dioxygenase: structures, spectra, redox and dioxygenase activity
    Ajaykamal, Tamilarasan
    Palaniandavar, Mallayan
    RSC ADVANCES, 2023, 13 (35) : 24674 - 24690
  • [45] [Mn(CO)3(bpy)(N-2-chlorobenzylbenzimidazole)] OTf complex as a new photoactivatable CO-releasing molecule
    Ustun, E.
    Dusunceli, S. Demir
    Ozdemir, I.
    BULGARIAN CHEMICAL COMMUNICATIONS, 2017, 49 : 50 - 56
  • [46] Mechanistic insights into the crucial roles of Glu76 residue in nickel-dependent quercetin 2,4-dioxygenase for quercetin oxidative degradation
    Yan, Xueyuan
    Song, Jinshuai
    Lu, Qianqian
    Li, Chunsen
    JOURNAL OF CATALYSIS, 2020, 387 : 73 - 83
  • [47] A co-releasing molecule, CORM-3, attenuates ischemia/reperfusion injury in a new model in pig liver
    Gringeri, E.
    Vadori, M.
    Motterlini, R.
    De Benedictis, G. M.
    Calabrese, F.
    Seveso, M.
    Mann, B. E. M.
    Cillo, U.
    Sacerdoti, D.
    Cozzi, E.
    XENOTRANSPLANTATION, 2007, 14 (05) : 449 - 449
  • [48] [Mn(CO)4{S2CNMe(CH2CO2H)}], a new water-soluble CO-releasing molecule
    Crook, Sian H.
    Mann, Brian E.
    Meijer, Anthony J. H. M.
    Adams, Harry
    Sawle, Philip
    Scapens, David
    Motterlini, Roberto
    DALTON TRANSACTIONS, 2011, 40 (16) : 4230 - 4235
  • [49] Mechanistic Studies of the Catalytic Reduction of CO2 to CO: Efficient CO-Releasing Si- and Ge-Based Catalysts
    Demissie, Taye B.
    Kessete, Jenbrie M.
    ACS OMEGA, 2022, 7 (05): : 4694 - 4702
  • [50] Cloning, sequence analysis; and expression of the Pseudomonas putida 33/1 1H-3-hydroxy-4-oxoquinoline 2,4-dioxygenase gene, encoding a carbon monoxide forming dioxygenase
    Max, N
    Betz, A
    Facey, S
    Lingens, F
    Hauer, B
    Fetzner, S
    BIOCHIMICA ET BIOPHYSICA ACTA-PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, 1999, 1431 (02): : 547 - 552