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Model systems for the CO-releasing flavonol 2,4-dioxygenase enzyme
被引:56
|作者:
Pap, Jozsef Sandor
[1
]
Kaizer, Jozsef
[1
]
Speier, Gabor
[1
]
机构:
[1] Univ Pannonia, Dept Chem, H-8201 Veszprem, Hungary
关键词:
Bioinorganic chemistry;
CO-releasing dioxygenases;
Flavonol;
Copper;
Biomimetic oxygenation;
DEPENDENT QUERCETIN 2,3-DIOXYGENASE;
CRYSTAL-STRUCTURE;
ASPERGILLUS-FLAVUS;
O-BS;
STOICHIOMETRIC OXYGENATION;
CATALYZED OXYGENATION;
FUNCTIONAL-ANALYSIS;
MECHANISM;
COPPER;
COMPLEXES;
D O I:
10.1016/j.ccr.2009.11.009
中图分类号:
O61 [无机化学];
学科分类号:
070301 ;
081704 ;
摘要:
In this review structural and reactivity studies on the co-ligand containing model complexes for the flavonol 2,4-dioxygenase (FDO) are covered. The main focus is on the relationship between the structural features of the copper-containing model complexes, and their activity in the enzyme-like reactions. Some radical initiated reactions and catalytic systems will also be discussed. (C) 2009 Elsevier B.V. All rights reserved.
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页码:781 / 793
页数:13
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