Facile, Template-Free Synthesis of Stimuli-Responsive Polymer Nanocapsules for Targeted Drug Delivery

被引：180
|
作者：
Kim, Eunju [1 ,2 ]
Kim, Dongwoo [1 ,2 ]
Jung, Hyuntae [1 ,2 ]
Lee, Jiyeong [1 ,2 ]
Paul, Somak [1 ,2 ]
Selvapalam, Narayanan [1 ,2 ]
Yang, Yosep [3 ]
Lim, Namseok [3 ]
Park, Chan Gyung [3 ]
Kim, Kimoon [1 ,2 ]
机构：
[1] Pohang Univ Sci & Technol, Natl Creat Res Initiat Ctr Smart Supramol, Dept Chem, Pohang 790784, South Korea
[2] Pohang Univ Sci & Technol, Div Adv Mat Sci, Pohang 790784, South Korea
[3] Pohang Univ Sci & Technol, Dept Mat Sci & Engn, Pohang 790784, South Korea
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2010年 / 49卷 / 26期
关键词：
cucurbituril; host-guest systems; nanostructures; polymerization; supramolecular chemistry; ENE CLICK CHEMISTRY; CUCURBITURIL; COMPLEXATION; DERIVATIVES; DENDRIMERS; CAPSULES; SURFACE; PHOTOPOLYMERIZATIONS; PHOTOINITIATORS; NANOPARTICLES;
D O I：
10.1002/anie.201000818
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
(Figure Presented) Open Sesame! A synthetic approach to stimuli-responsive polymer nanocapsules has been developed. The reductively labile polymer nanocapsule allows for not only facile, noncovalent surface modification but also the release of encapsulated cargo in response to a predefined redox stimulus in an intracellular environment. © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.
引用
收藏
页码：4405 / 4408
页数：4
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