An efficient synthesis of hexahydro oxaisoindolo[2,1-a]quinoline derivatives via the Diels-Alder reactions

被引：21

作者：

Kouznetsov, VV

Zubkov, FI

Cruz, UM

Voskressensky, LG

Mendez, LYV

Astudillo, L

Stashenko, EE

机构：

[1] Univ Talca, Inst Quim Recursos Nat, Lab Sintesis Organ, Talca, Chile

[2] Russian Peoples Friendship Univ, Dept Organ Chem, Moscow 117198, Russia

[3] Univ Ind Santander, Lab Sintesis Organ Fina, CIBIMOL, Escuela Quim, Bucaramanga, Colombia

来源：

LETTERS IN ORGANIC CHEMISTRY | 2004年 / 1卷 / 01期

关键词：

D O I：

10.2174/1570178043488572

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The straight forward synthesis of new carboxylic acids with hexahydro-oxaisoindolo[2.1-a]quinoline core from the 2,4-disustituted 1,2,3,4-tetrallydroquinolines bearing a furan fragment via the intramolecular Diels-Alder reaction has been proposed. It was demonstrated that synthesis of key precursors can be realized with excellent level of diastereoselectivity either by imino-Diels-Alder reaction or multi-component condensation approach.

引用

页码：37 / 39

页数：3

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