An efficient synthesis of hexahydro oxaisoindolo[2,1-a]quinoline derivatives via the Diels-Alder reactions

被引：21
|
作者：
Kouznetsov, VV
Zubkov, FI
Cruz, UM
Voskressensky, LG
Mendez, LYV
Astudillo, L
Stashenko, EE
机构：
[1] Univ Talca, Inst Quim Recursos Nat, Lab Sintesis Organ, Talca, Chile
[2] Russian Peoples Friendship Univ, Dept Organ Chem, Moscow 117198, Russia
[3] Univ Ind Santander, Lab Sintesis Organ Fina, CIBIMOL, Escuela Quim, Bucaramanga, Colombia
来源：
LETTERS IN ORGANIC CHEMISTRY | 2004年 / 1卷 / 01期
关键词：
D O I：
10.2174/1570178043488572
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The straight forward synthesis of new carboxylic acids with hexahydro-oxaisoindolo[2.1-a]quinoline core from the 2,4-disustituted 1,2,3,4-tetrallydroquinolines bearing a furan fragment via the intramolecular Diels-Alder reaction has been proposed. It was demonstrated that synthesis of key precursors can be realized with excellent level of diastereoselectivity either by imino-Diels-Alder reaction or multi-component condensation approach.
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收藏
页码：37 / 39
页数：3
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