NbCl5 as an Efficient Catalyst for the Synthesis of 1,5-Benzodiazepine Derivatives

被引：22

作者：

Gao, Shu-Tao ^{[1
]}

Liu, Wei-Hua ^{[1
]}

Ma, Jing-Jun ^{[1
]}

Wang, Chun ^{[1
]}

Liang, Qian ^{[1
]}

机构：

[1] Agr Univ Hebei, Coll Sci, Baoding 071001, Hebei, Peoples R China

来源：

SYNTHETIC COMMUNICATIONS | 2009年 / 39卷 / 18期

关键词：

1; 5-Benzodiazepines; ketones; NbCl5; o-phenylenediamines; PROMOTED SYNTHESIS; IONIC LIQUID; CYCLOADDITION; ALLYLATION; REAGENT; ACID; BENZOHETEROAZEPINE; TRIFLATE; GREEN;

D O I：

10.1080/00397910902752238

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,5-Benzodiazepine derivatives were synthesized in moderate to excellent isolated yields by the condensation reactions of o-phenylenediamine and ketones catalyzed by NbCl5 under mild conditions using n-hexane as solvent at 50 degrees C. This method is simple and effective with good yields.

引用

页码：3278 / 3284

页数：7

共 50 条

[31] 1,5-BENZODIAZEPINE DERIVATIVES WITH EXPECTED PSYCHOTROPIC ACTIVITY
NAWOJSKI, A
NAWROCKA, W
WILIMOWSKI, M
ORZECHOWSKAJUZWENKO, K
BARCZYNSKA, J
KEDZIERSKA, L
WOJEWODZKI, W
PRZYBYLSKA, E
FELSZTYNSKA, J
POLISH JOURNAL OF PHARMACOLOGY AND PHARMACY, 1979, 31 (06): : 615 - 622
[32] Efficient Synthesis and Biological Evaluation of a Novel Series of 1,5-Benzodiazepine Derivatives as Potential Antimicrobial Agents
An, Ying-shuang
Hao, Zhen-fang
Zhang, Xiu-jun
Wang, Lan-zhi
CHEMICAL BIOLOGY & DRUG DESIGN, 2016, 88 (01) : 110 - 121
[33] Sodium tetrachloroaurate(III) dihydrate-catalyzed efficient synthesis of 1,5-benzodiazepine and quinoxaline derivatives
Shi, Ren-xin
Liu, Yun-kui
Xu, Zhen-yuan
JOURNAL OF ZHEJIANG UNIVERSITY-SCIENCE B, 2010, 11 (02): : 102 - 108
[34] SYNTHESIS AND STRUCTURE DETERMINATION OF ISOMERIC 7-CHLORO-1,5-BENZODIAZEPINE AND 8-CHLORO-1,5-BENZODIAZEPINE DERIVATIVES
PENNINI, R
CERRI, A
TAJANA, A
NARDI, D
GIORDANO, F
JOURNAL OF HETEROCYCLIC CHEMISTRY, 1988, 25 (01) : 305 - 310
[35] Sodium tetrachloroaurate(III) dihydrate-catalyzed efficient synthesis of 1,5-benzodiazepine and quinoxaline derivatives
Ren-xin SHI
Journal of Zhejiang University-Science B(Biomedicine & Biotechnology), 2010, 11 (02) : 102 - 108
[36] A fast and efficient method for the synthesis of 1,5-benzodiazepine derivatives under solvent-free conditions
Shaabani, Ahmad
Maleki, Ali
IRANIAN JOURNAL OF CHEMISTRY & CHEMICAL ENGINEERING-INTERNATIONAL ENGLISH EDITION, 2007, 26 (04): : 93 - 97
[37] One pot solvent-free synthesis of 1,5-benzodiazepine derivatives
Langade, M., 1600, Journal of Chemical and Pharmaceutical Research, 3/668 Malviya Nagar, Jaipur, Rajasthan, India (05):
[38] Ytterbium Perfluorooctanesulfonate catalyzed synthesis of 1,5-benzodiazepine derivatives in fluorous solvents
Yi, Wen-Bin
Cai, Chun
SYNTHETIC COMMUNICATIONS, 2007, 37 (19-21) : 3827 - 3833
[39] A highly efficient synthesis of 3H-1,5-benzodiazepine derivatives using lanthanum(III) nitrate hexahydrate as a catalyst
Kumar, Rajesh
Joshi, Y. C.
JOURNAL OF THE INDIAN CHEMICAL SOCIETY, 2008, 85 (10) : 1045 - 1049
[40] A simple environmentally-friendly method for the selective synthesis of 1,5-benzodiazepine derivatives using zeolite catalyst
Hegedüs, A
Hell, Z
Potor, A
CATALYSIS LETTERS, 2005, 105 (3-4) : 229 - 232

← 1 2 3 4 5 →