Conformational control on remote stereochemistry in the intramolecular Pauson-Khand reactions of enynes tethered to homoallyl and homopropargyl alcohols

被引：10

作者：

Sezer, Serdar

Ozdemirhan, Devrim

Sahin, Ertan

Tanyeli, Cihangir ^{[1
]}

机构：

[1] Middle E Tech Univ, Dept Chem, TR-06531 Ankara, Turkey

[2] Abant Izzet Baysal Univ, Dept Chem, TR-14280 Bolu, Turkey

[3] Ataturk Univ, Dept Chem, TR-25240 Erzurum, Turkey

来源：

TETRAHEDRON-ASYMMETRY | 2006年 / 17卷 / 21期

关键词：

D O I：

10.1016/j.tetasy.2006.11.012

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

An intramolecular Pauson-Khand reaction of enynes derived from homoallyl and homopropargyl alcohols is described. 2-Furyl substituted homoallyl and homopropargyl alcohols are easily and efficiently resolved through enzymatic resolution in a high ee (93-99%) with a known stereochemistry. Each enantiomerically enriched enyne affords the conformationally most stable diastereomeric cyclopenta[c]pyran ring system. (c) 2006 Elsevier Ltd. All rights reserved.

引用

页码：2981 / 2986

页数：6

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