Rhodium-Catalyzed Regioselective Hydroformylation of Alkynes to α,β-Unsaturated Aldehydes Using Formic Acid

被引：18

作者：

Fan, Chao ^{[1
,2
]}

Hou, Jing ^{[1
,2
]}

Chen, Yu-Jia ^{[1
,2
]}

Ding, Kui-Ling ^{[3
]}

Zhou, Qi-Lin ^{[1
,2
]}

机构：

[1] Nankai Univ, Coll Chem, State Key Lab, Tianjin 300071, Peoples R China

[2] Nankai Univ, Coll Chem, Inst Elemento Organ Chem, Tianjin 300071, Peoples R China

[3] Chinese Acad Sci, Shanghai Inst Organ Chem, State Key Lab Organometall Chem, Shanghai 200032, Peoples R China

来源：

ORGANIC LETTERS | 2021年 / 23卷 / 06期

基金：

中国国家自然科学基金;

关键词：

CARBON; HYDROCARBOXYLATION;

D O I：

10.1021/acs.orglett.1c00234

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A rhodium-catalyzed hydroformylation of alkynes with formic acid was developed. The method provides alpha,beta-unsaturated aldehydes in high yield and E-selectivity without the need to handle toxic CO gas.

引用

页码：2074 / 2077

页数：4

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