An unusual cascade reaction of 4,5-dihydro-4,4-bis(trifluoromethyl)-2-phenyl-6,7-(4-chlorobenzo)[e]-1,3,2-dioxaphosphepin-5-one with chloral

被引：3

作者：

Mironov, Vladimir F. ^{[1
,2
]}

Borisova, Yuliya Yu. ^{[1
]}

Burnaeva, Liliya M. ^{[1
]}

Krivolapov, Dmitry B. ^{[2
]}

Litvinov, Igor A. ^{[2
]}

Zverev, Vladislav V. ^{[2
]}

Musin, Rashid Z. ^{[2
]}

Konovalova, Irina V. ^{[1
]}

机构：

[1] Kazan VI Lenin State Univ, AM Butlerov Chem Inst, Kazan 420008, Russia

[2] Russian Acad Sci, Kazan Sci Ctr, AE Arbuzov Organ & Phys Chem Inst, Kazan 420088, Russia

来源：

MENDELEEV COMMUNICATIONS | 2010年 / 20卷 / 01期

基金：

俄罗斯基础研究基金会;

关键词：

D O I：

10.1016/j.mencom.2010.01.017

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The reaction of 4,5-dihydro-4,4-bis(trifluoromethyl)-2-phenyl-6,7-(4-chlorobenzo)[e]-1,3,2-dioxaphosphepin-5-one with chloral (1:2) proceeds with evolving hexafluoroacetone and gives spiro{2-oxo-4-trichloromethyl-4,5-dihydro-2-phenyl-6,7-(4-chlorobenzo)[f]-1,3,2-dioxaphosphepine-5,2'-(3-trichloromethyl)oxirane) with a high stereoselectivity. Configuration of the four chiral centres (p(S)(2)C(S)(4)C(S)(5)C(S)5C(S)(3)'/(PRCRCRCR3)-C-2-C-4-C-5') was determined by a single crystal X-ray diffraction.

引用

页码：44 / 46

页数：3

共 42 条

[41] Five-membered 2,3-dioxo heterocycles: LXXXV. Synthesis of methyl 1-aryl-4,5-dioxo-3-(1-oxo-3-phenylprop-2-en-1-yl)-4,5-dihydro-1H-pyrrole-2-carboxylates and their reaction with 3-amino-5,5-dimethylcyclohex-2-en-1-ones. Molecular and crystalline structure of 4′-hydroxy-1′-(4-methoxyphenyl)-6,6-dimethyl-3′-(1-oxo-3-phenylprop-2-en-1-yl)-1-phenyl-6,7-dihydrospiro[indole-3,2′-pyrrole]-2,4,5′(1H,1′H,5H)-trione
P. S. Silaichev
V. O. Filimonov
P. A. Slepukhin
A. N. Maslivets
Russian Journal of Organic Chemistry, 2012, 48 : 561 - 565
[42] IMINOPHOSPHORANE-MEDIATED SYNTHESES OF [1,2,4]TRIAZOLO[5,1-C][1,2,4]TRIAZINES - THE UNEXPECTED FORMATION OF Z,Z-1,3-DIAZETIDINE-2,4-DI-IMINES - X-RAY MOLECULAR-STRUCTURE OF 7-(P-CHLOROANILINO)-8-(P-CHLOROPHENYL)-3-METHYL[1,2,4]TRIAZOLO[5,1-C][1,2,4]TRIAZIN-4(8H)-ONE AND OF 1,3-BIS(P-CHLOROPHENYL)-2,4-BIS-(6-METHYL-3-METHYLTHIO-5-OXO-4,5-DIHYDRO-1,2,4-TRIAZIN-4-YLIMINO)-1,3-DIAZETIDINET
MOLINA, P
ALAJARIN, M
SAEZ, JR
FOCESFOCES, MD
CANO, FH
CLARAMUNT, RM
ELGUERO, J
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1986, (12): : 2037 - 2049

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