Highly efficient one-pot synthesis of 2-arylmethyl N-substituted anilines via Yb(OTf)3 catalyzed three-component reaction

被引：2
|
作者：
Wang Li-Min [1 ]
Zhang Liang
Hu Liang
Tian He
机构：
[1] E China Univ Sci & Technol, Adv Mat Lab, Shanghai 200237, Peoples R China
[2] E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2007年 / 25卷 / 03期
关键词：
Yb(OTf)(3); 2-arylmethyl N-substituted aniline; aldehyde; 1-cyclohexen-2-one; amine;
D O I：
10.1002/cjoc.200790071
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
An efficient method has been developed for one-pot three-component coupling reactions of various aldehydes, 1-cyclohexen-2-one, and primary or secondary amines in the presence of a catalytic amount of Yb(OTf)(3) under mild conditions to afford the corresponding 2-arylmethyl N-substituted anilines in good yields. In addition, the catalyst was easily recovered and could be reused for at least four cycles without any loss of activity.
引用
收藏
页码：370 / 374
页数：5
相关论文
共 50 条
  • [11] Synthesis of substituted anilines via a gold-catalyzed three-component reaction
    Ueda, Hirofumi
    Yamamoto, Ryota
    Yamaguchi, Minami
    Tokuyama, Hidetoshi
    ORGANIC & BIOMOLECULAR CHEMISTRY, 2021, 19 (04) : 765 - 769
  • [12] Highly efficient one-pot three-component Mannich reaction in water catalyzed by heteropoly acids
    Azizi, N
    Torkiyan, L
    Saidi, MR
    ORGANIC LETTERS, 2006, 8 (10) : 2079 - 2082
  • [13] Yb(OTf)(3)-Catalyzed one-pot synthesis of beta-lactams from silyl ketene thioacetals by a two- or a three-component reaction
    Annunziata, R
    Cinquini, M
    Cozzi, F
    Molteni, V
    Schupp, O
    JOURNAL OF ORGANIC CHEMISTRY, 1996, 61 (23): : 8293 - 8296
  • [14] One-pot synthesis of substituted quinolines by iridium-catalyzed three-component coupling reaction
    Igarashi, T
    Inada, T
    Sekioka, T
    Nakajima, T
    Shimizu, I
    CHEMISTRY LETTERS, 2005, 34 (01) : 106 - 107
  • [15] New synthesis of 2-substituted azoles via a three-component one-pot reaction.
    Deng, YJ
    Hlasta, DJ
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2001, 222 : U47 - U47
  • [16] Synthesis of highly functionalized thiophenes by three-component and one-pot reaction
    Hassanabadi, Alireza
    Hosseini-Tabatabaei, Mohammad R.
    JOURNAL OF SULFUR CHEMISTRY, 2012, 33 (03) : 273 - 277
  • [17] Highly efficient synthesis of tetrasubstituted 2,3-dihydropyrans by three-component 'one-pot' reaction
    Li, Chao
    Cai, Liang-Zhen
    Liu, Xiao-Dong
    Zhu, Shi-Zheng
    Xing, Chun-Hui
    Lu, Long
    TETRAHEDRON LETTERS, 2016, 57 (20) : 2171 - 2174
  • [18] Highly Efficient One-Pot Three-Component Synthesis of Naphthopyran Derivatives in Water Catalyzed by Phosphates
    Essamlali, Younes
    Amadine, Othmane
    Maati, Houda
    Abdelouahdi, Karima
    Fihri, Aziz
    Zahouily, Mohamed
    Varma, Rajender S.
    Solhy, Abderrahim
    ACS SUSTAINABLE CHEMISTRY & ENGINEERING, 2013, 1 (09): : 1154 - 1159
  • [19] HIGHLY EFFICIENT ONE-POT, THREE-COMPONENT SYNTHESIS OF β-AMINOKETONES CATALYZED BY Fe(O2CCF3)3
    Zhang, Min
    Xiong, Biao
    Yang, Wei
    Chen, Ling
    Wu, Feng
    Wang, Quan
    Ding, Yuqiang
    SYNTHETIC COMMUNICATIONS, 2012, 42 (19) : 2831 - 2843
  • [20] The synthesis of 2-substituted azoles through a one-pot three-component reaction
    Deng, YJ
    Hlasta, DJ
    TETRAHEDRON LETTERS, 2002, 43 (02) : 189 - 192
12345