NOVEL SARS-COV-2 PANDEMIC TRANSMISSION WITH ONGOING ANTIVIRAL THERAPIES AND VACCINE DESIGN

被引:0
|
作者
Yameen, Muhammad [1 ]
Sattar, Sara [3 ]
Khalid, Ayesha [3 ]
Aslam, Muhammad Aamir [2 ]
Zafar, Nishat [2 ]
Saeed, Muhammad Hassan [4 ]
Arif, Muhammad Haseeb [4 ]
Jahangeer, Muhammad [1 ]
Qadeer, Azka [2 ]
Hussain, Shoukat [1 ]
Aamir, Muhammad [2 ]
Mukhtar, Sania [2 ]
Nasir, Huma [2 ]
Shahzad, Asif [1 ]
机构
[1] Govt Coll Univ, Dept Biochem, Faisalabad 38000, Pakistan
[2] Univ Agr Faisalabad, Inst Microbiol, Faisalabad 38000, Pakistan
[3] COMSATS Univ Islamabad, Dept Biosci, Islamabad, Pakistan
[4] Univ Punjab, Dept Microbiol & Mol Genet, Lahore, Pakistan
关键词
SARs-CoV-2; WHO; viral genome; COVID-19; SARS-COV; CORONAVIRUS; COVID-19; MERS;
D O I
10.21307/PM-2021.60.1.02
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Starting from the end of 2019 the new SARs-CoV-2 virus, in the period of a few months, had spread to 210 countries and its territories. The Wuhan wild animal market, in Hubei province, China is considered the epicenter of this pandemic. WHO declared the name COVID-19 to designate the disease caused by the SARS-CoV-2 virus. It is the third coronavirus pandemic after SARS in 2002-2003 and MERS-CoV in 2012. Genome sequencing of this new COVID-19/SARS-CoV-2 virus shows slight genetic diversity when compared to other coronaviruses. Owing to its pathogenesis, and less known replication cycle, no universal antiviral treatment can be applied and vaccine preparation is still a larger challenge. The present article will highlight transmission, pandemic status, genetic diversity current antiviral therapy, and vaccine trials for COVID-19.
引用
下载
收藏
页码:13 / 20
页数:8
相关论文
共 50 条
  • [21] The role of SARS-CoV-2 nucleocapsid protein in antiviral immunity and vaccine development
    Yu, Haiyun
    Guan, Fei
    Miller, Heather
    Lei, Jiahui
    Liu, Chaohong
    EMERGING MICROBES & INFECTIONS, 2023, 12 (01)
  • [22] Implications of the Novel Mutations in the SARS-CoV-2 Genome for Transmission, Disease Severity, and the Vaccine Development
    Akkiz, Hikmet
    FRONTIERS IN MEDICINE, 2021, 8
  • [23] Designed for a pandemic: Mitigating the risk of SARS-CoV-2 transmission through hospital design and infrastructure
    Kennedy, Brendan
    Ashokan, Anushia
    Lim, Chuan Kok
    Lagana, Diana
    Juraja, Marija
    Shaw, David
    INFECTION DISEASE & HEALTH, 2024, 29 (01) : 25 - 31
  • [24] Adaptation-Proof SARS-CoV-2 Vaccine Design
    Vishweshwaraiah, Yashavantha L.
    Hnath, Brianna
    Rackley, Brendan
    Wang, Jian
    Gontu, Abhinay
    Chandler, Morgan
    Afonin, Kirill A.
    Kuchipudi, Suresh, V
    Christensen, Neil
    Yennawar, Neela H.
    Dokholyan, Nikolay, V
    ADVANCED FUNCTIONAL MATERIALS, 2022, 32 (49)
  • [25] Novel SARS-CoV-2 variants: the pandemics within the pandemic
    Boehm, Erik
    Kronig, Ilona
    Neher, Richard A.
    Eckerle, Isabella
    Vetter, Pauline
    Kaiser, Laurent
    CLINICAL MICROBIOLOGY AND INFECTION, 2021, 27 (08) : 1109 - 1117
  • [26] Design, production and characterization of antiviral proteins targeting SARS-CoV-2
    Parreiras, S.
    Cruz, C. H.
    Valerio, M.
    Sousa, P. M. F.
    Soares, C. M.
    Vicente, J. B.
    Lousa, D.
    FEBS OPEN BIO, 2022, 12 : 160 - 160
  • [27] SARS-CoV-2 mucosal vaccine
    Stephanie Houston
    Nature Immunology, 2023, 24 : 1 - 1
  • [28] Inactivated vaccine for SARS-CoV-2
    Emma Risson
    Nature Reviews Immunology, 2020, 20 : 353 - 353
  • [29] SARS-CoV-2 mucosal vaccine
    Houston, Stephanie
    NATURE IMMUNOLOGY, 2023, 24 (01) : 1 - 1
  • [30] A VACCINE AGAINST SARS-COV-2
    Passi, Gouri Rao
    INDIAN PEDIATRICS, 2020, 57 (06) : 593 - 593