Microbial Transformation of Prochiral Ketones Using Rhizopus arrhizus

被引：0

作者：

Salokhe, Prabha R. ^{[1
]}

Salunkhe, Rajeshri S. ^{[1
]}

机构：

[1] Shivaji Univ, Dept Chem, Kolhapur 416004, Maharashtra, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2009年 / 21卷 / 06期

关键词：

Biotransformations; Transformation; Prochiral ketones; Rhizopus arrhizus; Bioreduction; Carbinols; ENANTIOMER; REDUCTION;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The various species Of Rhizopus arrhizus have been used tor microbial transformations of p-chloro, p-methyl and p-methoxy propiophenone to synthesize corresponding enantiomerically pure (S) alcohols in 7090 % ee. In a screening of various species of Rhizopus arrhizus for enantioselective reduction of propiophenone derivatives,. Rhizopus arrhizus NCIM-878 showed high activity for reduction of above prochiral ketones and it efficiently hydrolyzes the racemic acetate of p-methoxy propiophenone to corresponding (R) alcohol.

引用

页码：4333 / 4338

页数：6

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