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Synthesis, Characterization, and Antimicrobial Evaluation of Novel 4-Pyrrol-1-yl-5,6,7,8-tetrahydro-pyrido[4′,3′:4,5] Thieno[2,3-d]pyrimidine Derivatives
被引:12
|作者:
Parmar, Kokila
[1
]
Suthar, Bharat
[1
]
Suthar, Arun
[1
]
Maheta, Abhay
[2
]
机构:
[1] Hemchandracharya N Gujarat Univ, Dept Chem, Patan 384265, Gujarat, India
[2] Enum Nostrum Remedis, Bombay 400059, Maharashtra, India
关键词:
CHEMISTRY;
EXPLORATION;
UREAS;
D O I:
10.1002/jhet.190
中图分类号:
O62 [有机化学];
学科分类号:
070303 ;
081704 ;
摘要:
A series of novel 7-alkyl/aryl sulfonyl-4-pyrrol-1-yl-5,6,7,8-tetrahydro-pyrido[4',3':4,5]thieno[2,3-d] pyrimidine 6 were synthesized for evaluation of their antibacterial and antifungal activity. The structures were determined by IR, NMR, mass spectroscopy, and elemental analysis. They were screened for activities against bacterial and fungal strains.
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页码:975 / 979
页数:5
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