RETRACTED: The amine-catalysed Suzuki-Miyaura-type coupling of aryl halides and arylboronic acids (Retracted Article)

被引:17
|
作者
Xu, Lei [1 ]
Liu, Fu-Yue [1 ]
Zhang, Qi [1 ]
Chang, Wei-Jun [1 ]
Liu, Zhong-Lin [1 ]
Lv, Ying [2 ]
Yu, Hai-Zhu [2 ]
Xu, Jun [1 ]
Dai, Jian-Jun [1 ]
Xu, Hua-Jian [1 ]
机构
[1] Hefei Univ Technol, Anhui Prov Key Lab Adv Catalyt Mat & React Engn, Inst Ind & Equipment Technol, Sch Food & Biol Engn,Sch Chem & Chem Engn, Hefei, Peoples R China
[2] Anhui Univ, Dept Chem, Anhui Prov Key Lab Chem Inorgan Organ Hybrid Func, Hefei, Peoples R China
基金
中国国家自然科学基金;
关键词
PINCER COMPLEXES; METAL; PALLADIUM; DERIVATIVES; MECHANISMS; EFFICIENT; RECEPTOR; BIARYLS; ALKYNES;
D O I
10.1038/s41929-020-00564-z
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Suzuki-Miyaura coupling is a practical and attractive carbon-carbon bond formation reaction due to its high efficiency and wide functional group compatibility, but its industrial applications are limited because it is typically catalysed by expensive palladium-containing transition-metal complexes. Here we show a robust and chemoselective organocatalytic Suzuki-Miyaura-type coupling of aryl halides with arylboronic acids catalysed by amines. The utility and scope of this reaction were demonstrated by the synthesis of several commercially relevant small molecules and a selection of derivatives of pharmaceutical drugs.
引用
收藏
页码:71 / 78
页数:8
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